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Table 5 Tolerability of NVP-based HAART among the three groups.

From: Safety and tolerability of nevirapine-based antiretroviral therapy in HIV-infected patients receiving fluconazole for cryptococcal prophylaxis: a retrospective cohort study

Tolerability outcomes

Not receiving fluconazole

Receiving fluconazole

Pvalue

 

(n = 225)

400 mg/week (n = 392)

200 mg/day (n = 69)

 

On NVP-based HAART at six months

174 (77.3%)

309 (78.8%)

58 (84.1%)

0.532

Reasons of discontinuation

   

0.448

   Adverse events

26 (11.5%)

29 (7.4%)

3 (4.3%)

 

Skin rashes

25/26 (96.2%)

26/29 (89.7%)

3 of 3 (100.0%)

 

Hepatotoxicity

1/26 (2.8%)

3/29 (10.3%)

-

 

   Death

1 (0.4%)

8 (2.0%)

-

 

   Loss to follow-up

20 (8.9%)

39 (9.9%)

7 (10.1%)

 

   Refer

4 (1.8%)

7 (1.8%)

1 (1.4%)