Table 4 Head-to-head comparison between smear microscopy and phage assays
|  |  |  | Smear microscopy | Phage test | Difference (Phage – Microscopy) | |||
|---|---|---|---|---|---|---|---|---|
Study | Year | Sample size | Sensitivity | Specificity | Sensitivity | Specificity | Sensitivity | Specificity |
Commercial assays | ||||||||
Albay | 2003 | 192 | 0.58 (0.44,0.70) | 1.00 (0.97,1.00) | 0.88 (0.77,0.94) | 097 (0.92,0.99) | 0.30 | - 0.03 |
Albert | 2002 | 1618 | 0.62 (0.55,0.69) | 0.97 (0.96, 0.98) | 0.72 (0.66,0.78) | 0.99 (0.98,0.99) | 0.10 | 0.02 |
Alcaide | 2003 | 2048 | 0.73 (0.65,0.80) | 0.99 (0.98,0.99) | 0.58 (0.50,0.66) | 0.99 (0.99,0.99) | -0.15 | 0 |
Bellen | 2003 | 204 | 0.89 (0.82,0.95) | 0.60 (0.50,0.70) | 0.31 (0.22,0.41) | 0.86 (0.78, 0.92) | - 0.58 | 0.26 |
Butt | 2004 | 160 | 0.70 (0.57.0.81) | 0.95 (0.89,0.998) | 0.77 (0.64, 0.87) | 0.96 (0.90,0.99) | 0.07 | 0.01 |
Marei | 2003 | 38 | 0.64 (0.31,0.89) | 0.93 (0.76, 0.99) | 0.55 (0.23, 0.83) | 1.00 (0.87, 1.00) | -0.09 | .07 |
Mbulo | 2004 | 496 | 0.45 (0.32, 0.60) | 0.98 (0.91, 1.00) | 0.45 (0.32, 0.60) | 0.91 (0.82, 0.96) | 0 | -.07 |
Muzaffar | 2002 | 514 | 0.71 (0.65,0.77) | 0,94 (0.90,0.96) | 0.82 (0.76,0.86) | 0.98 (0.95,0.99) | 0.11 | 0.05 |
In- house assays | ||||||||
Mbulo | 2004 | 115 | 0.48 (0.29, 0.60) | 0.90 (0.81, 0.95) | 0.21,(0.08,0.40) | 0.91 (0.82,0.96) | -0.27 | 0.14 |
McNerney | 2004 | 496 | 0.60 (0.53,0.66) | 0.87(0.83,0.91) | 0.44 (0.37, 0.51) | 0.92 (0.89,0.95) | - 0.16 | 0.05 |