Preparation | Active agent(s) and concentration(s) | No neutralizers in sampling fluid | P-value (vs. reference)* | Neutralizers in sampling fluid | P-value (vs. reference)* | ||
---|---|---|---|---|---|---|---|
Samples without detectable test bacteria | Mean log10-reduction ± SD | Samples without detectable test bacteria | Mean log10-reduction ± SD | ||||
Product A | Ethanol (61%, w/w) chlorhexidine gluconate (1%, w/w) | 9 / 15 | 4.8 ± 1.5 | 0.02 | 0 / 15 | 2.7 ± 0.4 | 0.033 |
Reference alcohol | Iso-propanol (60%, v/v) | 0 / 15 | 3.7 ± 0.8 | n.a. | 0 / 15 | 3.5 ± 0.9 | n.a. |
Product B | Ethanol (85%, w/w) | 0 / 15 | 3.3 ± 0.7 | 0.44 | 0 / 15 | 3.3 ± 0.7 | 0.11 |