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Table 2 Association between vaginal micro-flora isolates and Nugent's vaginal flora categories and Amsel's diagnosis of bacterial vaginosis

From: Bacterial vaginosis, vaginal flora patterns and vaginal hygiene practices in patients presenting with vaginal discharge syndrome in The Gambia, West Africa

   Association with Nugent's vaginal flora categories Association with Amsel's diagnosis of BV
Isolate Nugent1 N2 %3 OR4 95% CI AOR5 95% CI Amsel6 N2 %3 OR4 95% CI AOR5 95% CI
Lactobacilli Normal flora 63 74.6 1 1      
  Interm. 54 35.2 0.18 0.08–0.41 0.18 0.08–0.41 Neg. 152 42.8 1 1
  BV 102 16.7 0.07 0.03–0.15 0.06 0.03–0.15 Pos. 67 26.9 0.49 0.26–0.92 1.11 0.52–2.38
  P 7    <0.001 <0.001 P 7    0.025 0.775
H 2 O 2 - Lactobacilli Normal flora 49 49.0 1 1      
  Interm. 49 14.3 0.17 0.07–0.46 0.17 0.07–0.47 Neg. 134 24.6 1 1
  BV 97 10.3 0.12 0.05–0.28 0.12 0.05–0.31 Pos. 61 13.1 0.46 0.20–1.07 0.94 0.36–2.49
  P 7    <0.001 <0.001 P 7    0.067 0.909
G vaginalis Normal flora 61 11.5 1 1      
  Interm. 54 35.2 4.19 1.59–11.0 3.96 1.50–10.5 Neg. 150 35.3 1 1
  BV 102 71.6 19.42 7.91–47.6 15.45 6.18–38.6 Pos. 67 68.7 4.01 2.17–7.42 2.21 1.10–4.44
  P 7    <0.001 <0.001 P 7    <0.001 0.026
Anaerobic isolates 8 Normal flora 21 0 1 1      
  Interm. 13 38.5 -9 -9 Neg. 43 18.6 1 1
  BV 31 48.4 -9 -9 Pos. 22 54.6 5.25 1.68–16.38 4.5 1.24–16.37
  P 7    0.001 - 10 P 7    0.003 0.018
Mycoplasma hominis Normal flora 60 13.3 1 1      
  Interm. 53 22.6 1.90 0.71–5.09 1.85 0.69–4.97 Neg. 148 18.9 1 1
  BV 102 25.5 2.22 0.93–5.29 2.00 0.80–4.96 Pos. 67 26.9 1.57 0.80–3.10 1.34 0.65–2.76
  P 7    0.184 0.282 P 7    0.188 0.436
  1. 1 Nugent's categories: normal flora (score 0–3), intermediate flora (score 4–6), BV (score 7–10).
  2. 2 Number of specimens.
  3. 3 Percentage positive for the isolate.
  4. 4 Crude Odds Ratio.
  5. 5 Odds Ratio adjusting for the other method of diagnosing BV.
  6. 6 Amsel's diagnosis 'positive' [pos.] if at least 3 out of 4 criteria present (homogenous adherent discharge; pH ≥ 4.6; whiff test positive; clue cells on 20% of epithelial cells); diagnosis is 'negative' [neg.] if <3 criteria present.
  7. 7 From X 2 test for unadjusted analysis. From likelihood ratio test when adjusting for the other diagnostic method.
  8. 8 Anaerobic isolates comprise Prevotella spp, Bacteroides spp, Peptostreptococcus spp and other anaerobes.
  9. 9 Not possible to calculate OR relative to normal flora due to lack of anaerobic isolation in normal subjects.
  10. 10 Not possible to fit model due to lack of anaerobic isolation in normal subjects.