| | |
Association with Nugent's vaginal flora categories
|
Association with Amsel's diagnosis of BV
|
|---|
|
Isolate
|
Nugent1
|
N2
|
%3
|
OR4 95% CI
|
AOR5 95% CI
|
Amsel6
|
N2
|
%3
|
OR4 95% CI
|
AOR5 95% CI
|
|---|
|
Lactobacilli
|
Normal flora
|
63
|
74.6
|
1
|
1
| | | | | |
| |
Interm.
|
54
|
35.2
|
0.18 0.08–0.41
|
0.18 0.08–0.41
|
Neg.
|
152
|
42.8
|
1
|
1
|
| |
BV
|
102
|
16.7
|
0.07 0.03–0.15
|
0.06 0.03–0.15
|
Pos.
|
67
|
26.9
|
0.49 0.26–0.92
|
1.11 0.52–2.38
|
| |
P
7
| | |
<0.001
|
<0.001
|
P
7
| | |
0.025
|
0.775
|
|
H
2
O
2
- Lactobacilli
|
Normal flora
|
49
|
49.0
|
1
|
1
| | | | | |
| |
Interm.
|
49
|
14.3
|
0.17 0.07–0.46
|
0.17 0.07–0.47
|
Neg.
|
134
|
24.6
|
1
|
1
|
| |
BV
|
97
|
10.3
|
0.12 0.05–0.28
|
0.12 0.05–0.31
|
Pos.
|
61
|
13.1
|
0.46 0.20–1.07
|
0.94 0.36–2.49
|
| |
P
7
| | |
<0.001
|
<0.001
|
P
7
| | |
0.067
|
0.909
|
|
G vaginalis
|
Normal flora
|
61
|
11.5
|
1
|
1
| | | | | |
| |
Interm.
|
54
|
35.2
|
4.19 1.59–11.0
|
3.96 1.50–10.5
|
Neg.
|
150
|
35.3
|
1
|
1
|
| |
BV
|
102
|
71.6
|
19.42 7.91–47.6
|
15.45 6.18–38.6
|
Pos.
|
67
|
68.7
|
4.01 2.17–7.42
|
2.21 1.10–4.44
|
| |
P
7
| | |
<0.001
|
<0.001
|
P
7
| | |
<0.001
|
0.026
|
|
Anaerobic isolates
8
|
Normal flora
|
21
|
0
|
1
|
1
| | | | | |
| |
Interm.
|
13
|
38.5
|
-9
|
-9
|
Neg.
|
43
|
18.6
|
1
|
1
|
| |
BV
|
31
|
48.4
|
-9
|
-9
|
Pos.
|
22
|
54.6
|
5.25 1.68–16.38
|
4.5 1.24–16.37
|
| |
P
7
| | |
0.001
|
-
10
|
P
7
| | |
0.003
|
0.018
|
|
Mycoplasma hominis
|
Normal flora
|
60
|
13.3
|
1
|
1
| | | | | |
| |
Interm.
|
53
|
22.6
|
1.90 0.71–5.09
|
1.85 0.69–4.97
|
Neg.
|
148
|
18.9
|
1
|
1
|
| |
BV
|
102
|
25.5
|
2.22 0.93–5.29
|
2.00 0.80–4.96
|
Pos.
|
67
|
26.9
|
1.57 0.80–3.10
|
1.34 0.65–2.76
|
| |
P
7
| | |
0.184
|
0.282
|
P
7
| | |
0.188
|
0.436
|
-
1 Nugent's categories: normal flora (score 0–3), intermediate flora (score 4–6), BV (score 7–10).
-
2 Number of specimens.
-
3 Percentage positive for the isolate.
-
4 Crude Odds Ratio.
-
5 Odds Ratio adjusting for the other method of diagnosing BV.
-
6 Amsel's diagnosis 'positive' [pos.] if at least 3 out of 4 criteria present (homogenous adherent discharge; pH ≥ 4.6; whiff test positive; clue cells on 20% of epithelial cells); diagnosis is 'negative' [neg.] if <3 criteria present.
-
7 From X
2 test for unadjusted analysis. From likelihood ratio test when adjusting for the other diagnostic method.
-
8 Anaerobic isolates comprise Prevotella spp, Bacteroides spp, Peptostreptococcus spp and other anaerobes.
-
9 Not possible to calculate OR relative to normal flora due to lack of anaerobic isolation in normal subjects.
-
10 Not possible to fit model due to lack of anaerobic isolation in normal subjects.
