Figure 4

Diagram of microdissected areas with corresponding PrP ^Sc immunolabelled sections and immunoblots taken at different time points throughout disease. Sections and immunoblots numbered; (1–3) -87V scrapie model; (4–5) -ME7 scrapie model; immunoblots show both PK treated (+) and untreated samples (-) normal brain (NB), numbers(at the foot of each gel lane) denote days post injection(dpi), terminal end point of disease(EP) and whole brain samples(WB)