Table 3 Factors associated with appropriate 3rd generation cephalosporin use at the POSGH, Jan- June 2000.
Variables | Appropriate Use (n = 62) | Inappropriate Use (n = 124) | Odds ratio (95% CI) | p Value |
|---|---|---|---|---|
Gender | ||||
Male | 25 | 37 | ||
Female | 53 | 71 | 0.91 (0.46–1.76) | 0.88 |
Age (mean ± SD) | 42 (18.73) | 46.61(21.63) | NS | |
Service | ||||
Gynecology | 3 | 24 | 6.58 (1.69–29.89) | p < 0.003 |
Orthopedics | 6 | 18 | 2.47 (0.081–7.00) | |
Medicine | 16 | 35 | 1.80 (0.81–4.01) | |
Surgery | 37 | 45 | 1.00 | |
Infection | ||||
Present | 44 | 60 | 2.61 (1.30–8.28) | p < 0.003 |
Absent | 18 | 64 | ||
Type of infection | ||||
Site unknown | 15 | 53 | 5.05 (1.45–18.10) | p < 0.007 |
Skin and soft tissue | 14 | 24 | 4.29 (0.94–20.71 | |
Respiratory | 6 | 13 | 3.13(.0.88–11.35) | |
Urinary tract | 10 | 7 | 1.00 | |
Therapy | ||||
Prophylactic | 17 | 39 | ||
Empiric | 45 | 81 | 1.27 (0.62–2.65) | p < 0.48 |
Multiple therapy | ||||
Single antibiotic | 18 | 73 | ||
2 or more antibiotics | 44 | 51 | 3.50(1.73–7.11) | p < 0.001 |