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Table 3 Geometric mean concentration (GMC, μg /ml) and 95 % confidence intervals (CI) of antibodies against pneumococcal serotypes included in the 11-valent pneumococcal vaccine given at 6, 10 and 14 weeks of age in Filipino infants

From: Safety and immunogenicity of three doses of an eleven-valent diphtheria toxoid and tetanus protein – conjugated pneumococcal vaccine in Filipino infants

Age

1

3

4

5

6B

7F

9V

14

18C

19F

23F

6 wk

(n = 49)

0.48 (0.34–0.68)

0.40 (0.30–0.54)

0.27 (0.19–0.38)

0.53 (0.37–0.77)

0.33 (0.24–0.46)

0.80 (0.58–1.12)

0.53 (0.39–0.77)

1.54 (1.03–2.53)

0.38 (0.26–0.52)

0.96 (0.64–1.45

0.49 (0.35–0.73)

18 wk

(n = 47)

15.23 (12.75–18.19)

4.87 (3.91–6.08)

23.41 (18.95–28.92)

12.49 (10.77–14.48)

1.12 (0.77–1.61)

8.87 (6.82–11.53)

7.69 (6.27–9.43)

2.18 (1.65–2.87)

4.50 (3.18–6.38)

16.11 (12.81–20.24)

3.89 (2.83–5.34)

  1. Serum sample withdrawn before vaccination at 6 weeks of age and 4 weeks after the third dose at 18 weeks of age