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Table 2 Spirometrya and sputum cell counts by Chlamydia pneumoniae DNA detection status among 92 patients with chronic obstructive pulmonary disease.

From: Smoking, season, and detection of chlamydia pneumoniaeDNA in clinically stable COPD patients

 

Number of Subjects

Entire Study Group

DNAb Present

DNA Absent

P-value (t-test)

Age in years (SD)

93

65.8 (10.7)

66.9 (11.9)

65.3 (10.3)

0.53

Smoking pack-years (SD)

93

43.1 (25.1)

48.9 (29.3)

41.8 (24.1)

0.22

FEV1 c (SD), L

93

1.35 (0.61)

1.34 (0.64)

1.36 (0.61)

0.88

FEV1 % predicted (SD)

93

46.9 (16.8)

44.3 (15.1)

48.0 (17.5)

0.33

FEV1/VCd % (SD)

93

45.7 (15.4)

42.6 (15.8)

47.0 (15.2)

0.22

Total cell count, 106/g (SD)

73

10.9 (15.4)

9.9 (12.5)

11.4 (16.8)

0.70

Viability, % (SD)

73

61.5 (24.2)

60.4 (22.7)

62.0 (25.0)

0.79

Squamous Epithelial, % (SD)

73

3.8 (8.6)

3.7 (5.3)

3.9 (10.0)

0.92

Neutrophils, % (SD)

73

63.6 (25.3)

60.6 (27.2)

65.2 (24.5)

0.46

Macrophages, % (SD)

73

25.6 (19.2)

26.4 (21.2)

25.2 (18.3)

0.78

Eosinophils, median % (Inter-quartile range)e

73

1.2 (3.0)

1.2 (3.7)

1.0 (2.9)

0.71e

  1. aAll spirometry after inhalation of 200 μg salbutamol. b C. pneumoniae DNA detected in peripheral blood mononuclear cells or induced sputum by nested polymerase chain reaction [14]. cFEV1: forced expiratory volume in 1 second. dVC: vital capacity. eComparison by Mann Whitney U test (SPSS).