Volume 14 Supplement 7

Proceedings of the 10th Edition of the Scientific Days of the National Institute for Infectious Diseases "Prof Dr Matei Bals"

Open Access

Etiology of UTI – pathogens involved and their sensitivity to antibiotics

  • Sorina Carp1Email author,
  • Anca Dumitrescu1,
  • Sorin Rugină1, 2,
  • Elena Dumea1, 2,
  • Maria Margareta Ilie1,
  • Stela Halichidis1, 2 and
  • Simona Claudia Cambrea1, 2
BMC Infectious Diseases201414(Suppl 7):P33

https://doi.org/10.1186/1471-2334-14-S7-P33

Published: 15 October 2014

Background

The study aims to evaluate the etiologic spectrum of urinary tract infections (UTI) and antibiotic sensitivity of isolates.

Methods

At the Infectious Disease Hospital in Constanța, between January 2014 and June 2014, urine cultures were performed in patients presenting urinary tract infections. Urine was seeded by loops calibrated technique on Columbia agar with 5% sheep blood and Drigalski agar. To identify the germs we used latex agglutination kits for Gram-positive germs and API galleries (BioMerieux) for Gram-negative bacilli. Antibiotics susceptibility testing was performed with the help of Kirby-Bauer disc diffusion method.

Results

Out of the total 805 urine samples performed, 160 turned out positive, isolating in 94 cases (58.7%) Escherichia coli, 25 cases (15.6%) Klebsiella spp., 12 cases (7%) Proteus spp., 15 cases (9.3%) Enterococcus spp., 7 cases (4.3%) Staphylococcus spp. and others – 7 cases (4.3%). E. coli was the most common etiological agent of UTI in women (64% of positive cases), men (42.3% of positive cases) and children (47% of positive cases).

Most of the isolated germs were highly susceptible to imipenem (94.4%) and fosfomycin (82.28%). Also, a good sensitivity to ceftriaxone (69.2%), quinolones (71.4%) and gentamicin (68.68%) was recorded. In addition, 56.6% of germs were sensitive to nalidixic acid and 56.6% to biseptol. We also noticed low sensitivity of germs to amoxicillin/clavulanic acid – 32.7%.

Conclusion

Escherichia coli was found in the highest percentage in urinary isolates, predominantly in women. There is an increased sensitivity of strains involved in urinary tract infections to fosfomycin – an affordable antibiotic that can be used in the treatment of these cases.

Authors’ Affiliations

(1)
Clinical Infectious Diseases Hospital of Constanța
(2)
Faculty of Medicine, “Ovidius” University

Copyright

© Carp et al; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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