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Table 7 Univariate and multivariate hazard ratios for the association between male circumcision and clearance of persistent genital HPV infection

From: Male circumcision and the incidence and clearance of genital human papillomavirus (HPV) infection in men: the HPV Infection in men (HIM) cohort study

  Any HPV Oncogenic HPV Non-Oncogenic HPV
    Univariatea Multivariateb    Univariatea Multivariatec    Univariatea Multivariated
Circumcision Inf./ Total % HR (95% CI) AHR (95% CI) Inf./ Total % HR (95% CI) AHR (95% CI) Inf./ Total % HR (95% CI) AHR (95% CI)
No 1474/ 3102 47.5 1.00 1.00 610/ 1128 54.1 1.00 1.00 864/ 1974 43.8 1.00 1.00
Yes 836/ 1686 49.6 0.94 (0.84 – 1.05) 0.99 (0.88 – 1.12) 324/ 645 50.2 0.76 (0.64 – 0.91) 0.84 (0.70 – 1.01) 512/ 1041 49.2 1.07 (0.92 – 1.25) 1.10 (0.94 – 1.29)
Total 2310/ 4788     934/ 1773     1376/ 3015    
  1. aAdjusted for age and country;
  2. bCox model stratified by country and age, and adjusted for lifetime number of female sexual partners, recent number of male anal sex partners, smoking status, HPV status at baseline, and six-month visit compliance status;
  3. cCox model stratified by country and age, and adjusted for lifetime number of female sexual partners, lifetime number of male anal sex partners, HPV status at baseline, and six-month visit compliance status;
  4. dCox model stratified by country and age, and adjusted for recent number of female sexual partners, recent number of male anal sex partners, smoking status, HPV status at baseline, and six-month visit compliance status.
  5. NOTE: Unit of analysis: infections; Excluded 120 infections that were a combination of persistent and transient infection; Abbreviations: Inf., infections; HR, hazard ratio; CI, confidence interval; AHR, adjusted hazard ratio.