Skip to main content

Table 2 Outcome in the 581 patients with confirmed typhoid categorised by age group

From: Risk factors for the development of severe typhoid fever in Vietnam

Covariate All ages <5 years 5-15 years ≥16 years p value1 p value2
n = 581 n = 44 n = 311 n = 226   
Severe or fatal disease 90 (15.5) 4 (9.1) 47 (15.1) 39 (17.3) 0.363 0.348
Gastrointestinal bleeding 43 (7.4) 1 (2.3) 22 (7.1) 20 (8.9) 0.334 0.287
Intestinal perforation 6 (1.0) 0 (0) 2 (0.6) 4 (1.8) 1.000 0.214
Encephalopathy 16 (2.8) 1 (2.3) 7 (2.3) 8 (3.5) 1.000 0.437
Myocarditis 12 (2.1) 0 (0) 9 (2.9) 3 (1.3) 0.609 0.384
Haemodynamic shock 5 (0.9) 0 (0) 0 (0) 5 (2.2) - 0.009
Renal impairment 4 (0.7) 0 (0) 0 (0) 4 (1.8) - 0.023
Hepatitis 29 (5.0) 1 (2.3) 18 (5.8) 10 (4.4) 0.488 0.617
Cholecystitis 4 (0.7) 0 (0) 3 (1.0) 1 (0.4) 1.000 1.000
Pneumonia 5 (0.9) 1 (2.3) 2 (0.6) 2 (0.9) 0.328 1.000
Pleural effusion 6 (1.0) 1 (2.3) 3 (1.0) 2 (0.9) 0.412 1.000
Severe anaemia 6 (1.0) 0 (0) 5 (1.6) 1 (0.4) 1.000 0.413
Blood transfusion 3 (0.5) 0 (0) 2 (0.6) 1 (0.4) 1.000 1.000
Death 3 (0.5) 0 (0) 0 (0) 3 (1.3) - 0.058
  1. 1Comparison of children < 5 years with children 5–15 years and 2 of children < 16 years with adults ≥ 16 years by chi square, Fisher’s exact or Mann–Whitney U test as appropriate.