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Table 1 Baseline characteristics

From: Clinical implications for patients treated inappropriately for community-acquired pneumonia in the emergency department

Variable Appropriate initial therapy (n = 187) Inappropriate initial therapy (n = 72) P value
Age, yrs: 58.1 ± 17.6 62.0 ± 15.3 0.103
Male, n (%): 109 (58.3) 40 (55.6) 0.690
Race, n (%):    
 Caucasian 86 (46.0) 31 (43.1) 0.779
 African-American 98 (52.4) 40 (55.6)  
 Other 3 (1.6) 1 (1.4)  
CURB65 1.9 ± 1.4 2.1 ± 1.2 0.348
Charlson comorbidity score 4.5 ± 3.3 5.4 ± 1.2 0.090
Coexisting conditions, n (%):    
 Coronary artery disease 34 (18.2) 14 (19.4) 0.815
 Congestive heart failure 56 (29.9) 31 (43.1) 0.045
 Peripheral vascular disease 13 (7.0) 13 (18.1) 0.008
 Cerebral vascular accident 18 (9.6) 10 (13.9) 0.322
 Dementia 4 (2.1) 0 (0.0) 0.578
 Chronic obstructive pulmonary disease 93 (49.7) 48 (66.7) 0.014
 Cirrhosis 23 (12.3) 6 (8.3) 0.364
 Diabetes 57 (30.5) 24 (33.3) 0.657
 Chronic kidney disease 20 (10.7) 16 (22.2) 0.016
 Underlying malignancy 32 (17.1) 12 (16.7) 0.932
 HIV positive 1 (0.5) 0 (0.0) 1.000
Healthcare-associated risk factors, n (%):    
 Hospitalized in preceding 90 days 36 (19.3) 22 (30.6) 0.051
 Long-term care resident 2 (1.1) 7 (9.7) 0.002
 Chronic hemodialysis 3 (1.6) 6 (8.3) 0.016
 Immunocompromised 38 (20.3) 17 (23.6) 0.562
 Previous antibiotics 43 (23.0) 28 (38.9) 0.010
Number of healthcare risk factors: 0.7 ± 0.9 1.1 ± 1.0 <0.001
Healthcare-associated infection: 79 (42.2) 50 (69.4) <0.001
ICU admission, n (%): 52 (27.8) 29 (40.3) 0.052
Respiratory failure, n (%):    
 None 142 (75.9) 51 (70.8) 0.630
 Intubation/mechanical ventilation 39 (20.9) 19 (26.4)  
 Mask ventilation 6 (3.2) 2 (2.8)  
Hypotension, n (%): 110 (58.8) 45 (62.5) 0.589
  1. Values are expressed as mean ± SD. CURB65 = confusion of new onset, urea greater than 7 mmol/l, respiratory rate of 30 breaths per minute or greater, blood pressure less than 90 mmHg systolic or diastolic blood pressure 60 mmHg or less, age 65 or older; HIV = human immunodeficiency virus; ICU = intensive care unit. The Charlson comorbidity score predicts the ten-year mortality for a patient who may have a range of comorbid conditions, such as heart disease, AIDS, or cancer (a total of 22 conditions).