Table 1 Demographic and clinical characteristics of patients initiated on MDR-TB treatment
| Â | Hearing loss by type of diagnosis | ||||
|---|---|---|---|---|---|
Variables | All patients n = 437 n (%) | No hearing loss n = 167 (38.2%) n (%) | Hearing loss confirmed by audiogram n = 147 (33.6%) n (%) | Clinical diagnosis of hearing loss n = 123 (28.2%) n (%) | |
Sex | Female | 197 (45.1) | 71 (42.5) | 63 (42.9) | 63 (51.2) |
Male | 240 (54.9) | 96 (57.5) | 84 (57.1) | 60 (48.8) | |
Age category in years | 15 – 19 | 28 (6.4) | 19 (11.4) | 6 (4.1) | 3 (2.4) |
20 – 29 | 85 (19.5) | 41 (24.6) | 19 (12.9) | 25 (20.3) | |
30 – 39 | 127 (29.0) | 40 (24.0) | 47 (32.0) | 40 (32.5) | |
40 – 49 | 100 (22.9) | 29 (17.4) | 44 (29.9) | 27 (22.0) | |
50 – 59 | 65 (14.9) | 25 (15.0) | 23 (15.7) | 17 (13.8) | |
≥ 60 | 32 (7.3) | 13 (7.8) | 8 (5.4) | 11 (8.9) | |
MDR-TB clinic | Clinic 1 | 101(23.0) | 36 (21.6) | 27 (18.4) | 38 (30.9) |
Clinic 2 | 218 (50.0) | 82 (49.1) | 78 (53.1) | 58 (47.1) | |
Clinic 3 | 35(8.0) | 9 (5.4) | 14 (9.2) | 12 (9.8) | |
Clinic 4 | 40(9.2) | 17 (10.2) | 10 (6.8) | 13 (10.6) | |
Clinic 5 | 43(9.8) | 23 (13.8) | 18 (12.2) | 2 (1.6) | |
History of prior TB treatment | Never treated for TB before | 27 (6.2) | 13 (7.8) | 8 (5.4) | 6 (4.9) |
New TB regimen | 142 (32.5) | 59 (35.3) | 38 (25.9) | 45 (36.6) | |
Retreatment regimen | 256 (58.6) | 95 (56.9) | 94 (64.0) | 67 (54.5) | |
*Treated for MDR-TB | 12 (2.7) | 0 (0.0) | 7 (4.8) | 5 (4.1) | |
Outcome | Completed | 97 (22.2) | 24 (14.4) | 48 (32.7) | 25 (20.3) |
Cured | 131 (30.0) | 36 (21.6) | 69 (46.9) | 26 (21.1) | |
Death | 53 (12.1) | 29 (17.4) | 10 (6.8) | 14 (11.4) | |
Lost to follow up | 10 (2.3) | 4 (2.4) | 3 (2.1) | 5 (4.1) | |
Failure | 22 (5) | 7 (4.3) | 5 (3.4) | 8 (6.5) | |
On treatment | 124 (28.4) | 67 (40.1) | 12 (8.2) | 45 (36.6) | |
HIV | HIV-uninfected | 149 (34.1) | 64 (38.3) | 42 (28.6) | 43 (35.0) |
HIV-infected | 288 (65.9) | 103 (61.7) | 105 (71.4) | 80 (65.0) | |
On anti-retroviral therapy | No | 19 (7.0) | 10 (9.7) | 4 (3.8) | 5 (6.2) |
Yes | 267 (93.0) | 93 (90.3) | 101 (96.2) | 73 (93.8) | |
CD + T 4 cell count cells/milliliter (mL) category | < 50 cells/mL | 44 (17.0) | 16 (15.6) | 16 (15.2) | 12 (15.0) |
50 – 199 cells/mL | 52 (20.2) | 17 (16.5) | 21 (20.0) | 14 (17.5) | |
200 – 350 cells/mL | 96 (37.2) | 32 (31.0) | 38 (36.2) | 26 (32.5) | |
> 350 cells/mL | 66 (25.6) | 38 (36.9) | 30 (28.6) | 28 (35.0) | |