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Table 3 Cytokine production of splenocytes induced by STAg

From: Evaluation of immuno-efficacy of a novel DNA vaccine encoding Toxoplasma gondiirhoptry protein 38 (TgROP38) against chronic toxoplasmosis in a murine model

Groups Cytokine production
IFN-γ IL-2 IL-4 IL-10
Blank control 47.3 ± 16.6 12.7 ± 8.0 11.6 ± 9.5 477.3 ± 87.5
pVAX I 34.9 ± 11.2 12.4 ± 11.8 12.1 ± 3.4 322.5 ± 179.2
PBS 36.4 ± 4.8 11.3 ± 6.0 13.3 ± 1.8 356.1 ± 175.3
pVAX-ROP38 575.2 ± 123.0*** 195.3 ± 28.4* < 5 48.7 ± 24.3***
  1. STAg soluble tachyzoite antigens.
  2. Data are presented as the mean ± SD (n = 3).
  3. *represents statistically significant difference (P < 0.05).
  4. ***represents statistically highly significant difference (P < 0.01).