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Table 1 Characteristics of the patients with pulmonary Mycobacterium avium complex disease with or without sputum conversion

From: The influence of environmental exposure on the response to antimicrobial treatment in pulmonary Mycobacterial avium complex disease

Variable Patients with sputum conversion (n = 52) Patients without sputum conversion (n = 20) P value
Age, years 61.5 ± 10.2 62.3 ± 10.8 0.85
Gender, female (%) 38 (73.1) 16 (80.0) 0.54
Underlying disease    
Lung disease 12 (23.1) 7 (35.0) 0.30
 COPD 3 (5.8) 1 (5.0) >0.99
 Asthma 3 (5.8) 1 (5.0) >0.99
 Previous tuberculosis 2 (3.9) 3 (15.0) 0.13
 Previous malignant disease 11 (21.2) 1 (5.0) 0.16
 Diabetes mellitus 5 (9.6) 1 (5.0) >0.99
 Collagen vascular disease 6 (11.5) 3 (15.0) 0.70
Immunosuppressive agents 2 (3.9) 3 (15.0) 0.13
Inhaled corticosteroid 2 (3.9) 0 (0.0) >0.99
Smoking status (ex or current) 11 (21.2) 3 (15.0) 0.74
Alcohol drinking habit 14 (26.9) 3 (15.0) 0.36
Environmental exposure    
 Low soil exposure before treatment 39 (75.0) 12 (60.0) 0.21
 Low soil exposure during treatment 44 (84.6) 13 (65.0) 0.10
 Low soil exposure during observation 37 (71.2) 10 (50.0) 0.09
 Bathing (≥1 per day) 50 (96.2) 18 (90.0) 0.31
 Shower use in a bathroom 41 (78.9) 14 (70.0) 0.43
 Swimming in a pool 2 (3.9) 0 (0.0) >0.99
Laboratory findings    
Negative smear 37 (71.2) 7 (35.0) 0.005
M. avium 39 (75.0) 17 (85.0) 0.60
M. intracellulare 12 (23.1) 3 (15.0)  
M. avium + M. intracellulare 1 (1.9) 0 (0.0)  
Radiographic findings    
 Any size of cavity 22 (42.3) 13 (65.0) 0.08
 Large cavity (≥2 cm) 7 (13.5) 8 (40.0) 0.02
 Bronchiectasis 46 (88.5) 19 (95.0) 0.66
Total length of follow-up time, months 55.6 ± 21.2 49.1 ± 16.4 0.28
  1. COPD, chronic obstructive pulmonary disease. The data show either the numbers (%) of patients or the means ± standard deviations. Low soil exposure is defined as no exposure or less than 2 hours per week of soil-related activities.