Figure 1

Neighbour-joining tree of T . muris homologues of RXR proteins. (A) The human RXRα protein sequence was queried against the T. muris gene set 2.1 (Feb 2013). The most significant four matches were aligned against representatives of the RXR gene family, (including sequences from other nematodes annotated as RXR homologues) and representatives of the related NR2F gene family. The more distantly related C. elegans protein NHR-49 was used as an outgroup. The phylogenetic tree shows that T. muris has a single orthologue of the RXR proteins, TMUE_s0189001000. (B) Alignment showing conservation of the DNA-binding domain. (C) Alignment showing conservation within the ligand-binding domain.