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Table 1 Characteristics of patients with infections or colonization due to XDR P. aeruginosa ; Bambino Gesù Children’s Hospital, 2011–2012 (N: 27)

From: An outbreak of extremely drug-resistant Pseudomonas aeruginosain a tertiary care pediatric hospital in Italy

  Bacteremia Other infections Colonization Total
Number of patients 12 6 9 27
  N (%) N (%) N (%) N (%)
Age     
Median 11.5 15 11 12
Range (2;24) (3;27) (1;16) (1;27)
Gender     
Male 4 (33.3%) 2 (33.3%) 5 (55.6%) 11 (40.7%)
Female 8 (66.7%) 4 (66.6%) 4 (44.4%) 16 (59.3%)
Diagnosis     
Leukemia/lymphoma 11 (91.7%) 4 (66.6%) 5 (55.6%) 20 (74.1%)
Solid tumor 0 0 1 (11.1%) 1 (3.7%)
Marrow failure 0 1 (16.6%) 0 1 (3.7%)
Inborn error 1 (8.3%) 1 (16.6%) 3 (33.3%) 5 (18.5%)
Chemotherapy     
Yes 8 (66.7%) 1 (16.6%) 3 (33.3%) 12 (44.4%)
No 4 (33.3%) 5 (83.3%) 6 (66.7%) 15 (55.6%)
HSCT     
Yes 4 (33.3%) 1 (16.6%) 1 (11.1%) 6 (22.2%)
No 8 (66.7%) 5 (83.3%) 8 (88.9%) 21 (77.8%)
Neutropenia (severity)     
<100 WBC/mm 3 10 (83.3%) 1 (16.6%) 1 (11.1%) 12 (44.4%)
100-500 WBC/mm 3 2 (16.7%) 0 0 2 (7.4%)
>500-1000 WBC/mm 3 0 0 1 (11.1%) 1 (3.7%)
>1000 WBC/mm 3 0 5 (83.3%) 7 (77.8%) 12 (44.4%)
Outcome     
 Died 8 (66.7%) 0 0 8 (29.6%)
 Alive 4 (33.3%) 6 (100%) 9 (100%) 19 (70.4%)
  1. WBC: white blood cells; HSCT: Hematopoietic stem cell transplantation.