Table 1 Reporting criteria for gram-negative bacteria, Hesse, Germany

1.

Every detection of a carbapenemase by molecular methodology ¹

2.

Phenotypic resistance tests (culture + antibiogram)

a) Pseudomonas aeruginosa

If resistant to all three of the following antibiotics:

Imipenem, meropenem and ceftazidime

b) Enterobacteriaceae (if not mentioned elsewhere)

If resistant to at least one of the following antibiotics:

Imipenem, meropenem or ertapenem

c) Proteus spp.

Morganella spp.

Providencia spp.

Serratia spp .

In case of resistance to imipenem and resistance to ertapenem or meropenem (an isolated increase of the MIC for imipenem together with normal MICs for meropenem and – if performed – for ertapenem does not require reporting)

d) Acinetobacter baumannii-complex

Enterobacter spp.

Citrobacter spp.

In case of resistance to imipenem or meropenem. (isolated resistance to ertapenem does not require reporting)

Not to be reported are species with intrinsic carbapenem-resistance. These include:

Stenotrophomonas maltophilia

Elizabethkingia meningoseptica

Chryseobacterium indologenes

Burkholderia cepacia