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Table 1 Reporting criteria for gram-negative bacteria, Hesse, Germany

From: Burden of carbapenem-resistant organisms in the Frankfurt/Main Metropolitan Area in Germany 2012/2013 – first results and experiences after the introduction of legally mandated reporting

1. Every detection of a carbapenemase by molecular methodology 1
2. Phenotypic resistance tests (culture + antibiogram)
  a) Pseudomonas aeruginosa
  If resistant to all three of the following antibiotics:
  Imipenem, meropenem and ceftazidime
  b) Enterobacteriaceae (if not mentioned elsewhere)
  If resistant to at least one of the following antibiotics:
  Imipenem, meropenem or ertapenem
  c) Proteus spp.
  Morganella spp.
  Providencia spp.
  Serratia spp .
  In case of resistance to imipenem and resistance to ertapenem or meropenem (an isolated increase of the MIC for imipenem together with normal MICs for meropenem and – if performed – for ertapenem does not require reporting)
  d) Acinetobacter baumannii-complex
  Enterobacter spp.
  Citrobacter spp.
In case of resistance to imipenem or meropenem. (isolated resistance to ertapenem does not require reporting)
Not to be reported are species with intrinsic carbapenem-resistance. These include:
Stenotrophomonas maltophilia
Elizabethkingia meningoseptica
Chryseobacterium indologenes
Burkholderia cepacia
  1. 1Laboratories are encouraged but not obliged to type carbapenem-resistant bacteria, analyses are offered free of charge by the national reference centre.