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Table 1 Characteristics of case series and RCT studies including in the qualitative analysis, according to treatment target (initial, gram-positive and gram-negative rods) and the patient’s renal basal disease

From: Efficacy of antibiotic therapy for peritoneal dialysis-associated peritonitis: a proportional meta-analysis

Study All studies Initial treatment/Negative culture Gram + Gram -
Total of studies (case series and RCTs) 84 [15-98] 44 [15-24,26,28,34,40,55,57,60-87] 36 [15,18,20-25,29,30,33-37,42,44,48,50,54,55,57,63,75,77,85,86,88-95] 32 [15,18,20,22,23,25,,31,32,35-37,39,41,45-47,49,50,52,55,57,63,69,77,78,86,91,93,96-98]
No. of patients/No. of episodes 9.268/16.109 4.411/7.315 3,526/6,259 2,549/4,925
Basal renal disease     
Branchio-oto-renal syndrome 1 0 0 0
Chronic tubulointerstitial disease 2 1 1 0
Diabetes 51 16 14 10
Glomerulonephritis 33 12 10 6
Gouty 1 1 0 0
Hemolytic-uremic syndrome 1 0 0 0
Hypertension 21 13 8 5
IgA nephropathy 1 1 0 0
Interstitial nephritis 3 1 0 0
Systemic lupus 5 2 1 1
Malignancy 2 0 1 0
Multiple myeloma 1 0 0 0
Nephrosclerosis 2 2 2 0
Obstruction/Reflux 15 5 4 4
Others/unknown 25 11 8 3
Pyelonephritis 4 3 1 1
Policystic kidney disease 24 8 8 5
Renal artery stenosis 1 1 0 0
Renovascular 12 3 1 1
Systemic autoimmune disease 2 2 1 0
Comorbidities     
AIDS 1 1 0 0
Cerebrovascular disease 7 1 2 0
Chronic lung disease 7 1 3 1
Connective tissue disorder 1 1 1 0
Congestive heart failure 2 1 1 0
Coronary heart disease 9 1 4 1
Current smoker 4 0 1 0
Dementia 2 1 1 0
Diabetes 16 6 8 5
Hemiplegia 2 1 1 0
Mild liver disease 2 1 1 0
Moderate or severe liver disease 3 2 1 0
Peptic ulcer disease 2 1 1 0
Peripheral vascular disease 9 1 2 0
Secondary hyperparathyroidism 1 0 1 1
Any Tumor, Leukemia, Lymphoma 4 2 3 1
Type of dialysis     
CAPD 50 32 24 23
APD 11 7 7 7
Not reported 37 9 11 9
Any change from APD to CAPD NR NR NR NR
Mean age (years) 57,36 55,65 58,44 56,53
  1. NR = not reported; CAPD = continuous ambulatory peritoneal dialysis; APD = automated peritoneal dialysis; RCT = randomized clinical trial.