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Table 2 CLART results for 5,068 samples, by age, screening history, cytology, and HC2 results

From: HPV prevalence and genotype distribution in a population-based split-sample study of well-screened women using CLART HPV2 Human Papillomavirus genotype microarray system

  Outcomes on CLART, N (%)
Any high-risk HPV genotype (%)a Negative on high-risk HPV genotypes (%)b Only low-risk HPV genotypes (%)a Invalid (%) Total (%)
Total 1,274 (25.1%) 3,782 (74.6%) 622 (12.3%) 12 (0.2%) 5,068 (100%)
Age (years)      
16-22 99 (61.1%) 63 (38.9%) 20 (12.3%) 0 (0.0%) 162 (100%)
23-29 608 (39.6%) 926 (60.3%) 216 (14.1%) 1 (0.1%) 1,535 (100%)
30-39 345 (22.6%) 1,176 (77.1%) 171 (11.2%) 4 (0.3%) 1,525 (100%)
40-49 135 (13.6%) 851 (85.8%) 119 (12.0%) 6 (0.6%) 992 (100%)
50-59 54 (10.7%) 452 (89.2%) 55 (10.8%) 1 (0.2%) 507 (100%)
60-65 24 (10.3%) 210 (89.7%) 25 (10.7%) 0 (0.0%) 234 (100%)
>65 9 (8.0%) 104 (92.0%) 16 (14.2%) 0 (0.0%) 113 (100%)
Screening history      
Primary samplec 1,024 (23.2%) 3,375 (76.5%) 528 (12.0%) 11 (0.2%) 4,410 (100%)
Follow-up sample 250 (38.0%) 407 (61.9%) 94 (14.3%) 1 (0.2%) 658 (100%)
Cytology      
Normal 1,001 (21.4%) 3,658 (78.3%) 561 (12.0%) 12 (0.3%) 4,671 (100%)
ASCUS 72 (58.5%) 51 (41.5%) 18 (14.6%) 0 (0.0%) 123 (100%)
LSIL 103 (72.5%) 39 (27.5%) 35 (24.6%) 0 (0.0%) 142 (100%)
≥HSIL 97 (91.5%) 9 (8.5%) 5 (4.7%) 0 (0.0%) 106 (100%)
≥ASCUS 272 (73.3%) 99 (26.7%) 58 (15.6%) 0 (0.0%) 371 (100%)
Inadequate 1 (3.8%) 25 (96.2%) 3 (11.5%) 0 (0.0%) 26 (100%)
HC2 d      
Positive 874 (84.4%) 160 (15.5%) 111 (10.7%) 1 (0.1%) 1,035 (100%)
Negative 399 (9.9%) 3,619 (89.8%) 510 (12.7%) 11 (0.3%) 4,029 (100%)
  1. Abbreviations: ASCUS atypical squamous cells of undetermined significance, HC2 Hybrid Capture 2 assay, HPV Human Papillomavirus, ≥HSIL high-grade intraepithelial lesions or worse, LSIL low-grade squamous intraepithelial lesions.
  2. aThirteen high-risk and probably high-risk genotypes, according to the classification reported by IARC [2].
  3. bNone of the 13 high-risk or probably high-risk genotypes detected.
  4. cPredominantly screening samples, including a small proportion of samples taken for indication.
  5. dFour samples were not tested with HC2.