Figure 3

Simulated seasonal fluctuation in influenza infections. The light grey solid curve shows influenza A and B infections in scenario 1 where only TIV is used, the dark grey dashed curve shows those in scenario 2 where TIV immunisation of children 2 to 17 years old is replaced in 2012 by LAIV immunisation and where childhood vaccination coverage with LAIV is subsequently increased up to 50% in three annual steps.