Skip to main content

Table 1 Clinical and virological characteristics of 25 studied patients infected with genotype 1b

From: Deep sequencing of hepatitis C virus hypervariable region 1 reveals no correlation between genetic heterogeneity and antiviral treatment outcome

 

Treatment responders SVR+, n = 12

Treatment non-responders SVR-, n = 13

P

Complete early viral response (cEVR)

12

0

-

Age (years)*

42.6 ± 17.9

50.1 ± 12.4

NS

Sex (M/F)

6/6

7/6

NS

Alanine aminotransferase levels [U/l]*

95.9 ± 74.1

109.2 ± 50.1

NS

Liver histology*, §

   

Grading

1.1 ± 0.4

1.1 ± 0.4

NS

Staging

1.3 ± 1.3

1.7 ± 0.8

NS

Pretreatment viral load (IU/ml)* , **

1.2 × 106 ± 1.2 × 106

1.5 × 106 ± 1.2× 106

NS

  1. *mean ± SD.
  2. **measured by RealTime HCV assay (Abbott), sensitivity: 12 IU/mL.
  3. §according to the METAVIR Histologic Scoring System.