Agreement between QuantiFERON®-TB Gold In-Tube and the tuberculin skin test and predictors of positive test results in Warao Amerindian pediatric tuberculosis contacts

Table 6 Results of multivariable logistic GEE regression analysis for the presence of TB sequelae on chest X-rays vs. normal chest X-rays at inclusion*

TB sequelae on CXR	Odds ratio	95% CI	p-value
IFN-γ level, IU/ml**	1.05	1.0-1.1	0.049
TST induration diameter, mm	0.95	0.84-1.08	0.44
Age, years	1.3	1.0-1.6	0.029
Sex, male vs. female	1.8	1.0-3.0	0.034
Malnourished	0.39	0.15-1.0	0.055
BCG vaccination	2.7	1.2-6.4	0.020
Duration of exposure, ≥12 h/day vs. <12 h/day	0.90	0.55-1.5	0.69

*Individuals who had active TB, indeterminate QFT-GIT results and those in whom a CXR and/or QFT-GIT was not performed (n = 33) were excluded from this analysis. A total of 55/130 remaining household contacts had radiological features of TB sequelae. Of these, 34 had calcifications as the lone abnormality.
**The level of IFN-γ (IU/ml) in the QFT TB antigen-stimulated plasma sample with that for the negative control subtracted.

ISSN: 1471-2334