Table 4 HBV serological and virological data in pregnant and non-pregnant AHB patients at admission, discharge and final follow-up
From: Clinical features and outcome of acute hepatitis B in pregnancy
Variables | Non-pregnant AHB patients N = 87 | Pregnant AHB patients N = 22 | P |
|---|---|---|---|
At admission | |||
Days from disease onset to examination | 11.8 ± 7.3 | 11.3 ± 4.1 | 0.70 |
HBsAg positive | 6 (93.1%) | 22 (100%) | 0.21 |
HBsAg > 250 IU/mL | 45 (51.7%) | 17 (77.3%) | 0.03 |
HBsAg seroconversion | 3 (3.44%) | 0 (0%) | 0.38 |
HBeAg positive | 52 (59.8%) | 19 (86.4%) | 0.02 |
HBeAg seroconversion | 33 (37.9%) | 2 (9.1%) | 0.01 |
HBV DNA (log10 copies/mL) | 3.49 (3.0-7.14) | 3.49 (3.0-4.93) | 0.69 |
HBV DNA >1000 copies/mL | 55 (63.2%) | 17 (77.3%) | 0.21 |
At discharge | |||
Days from disease onset to examination | 38.6 ± 11.9 | 34.2 ± 7.1 | 0.11 |
HBsAg positive | 54 (62.1%) | 19 (86.4%) | 0.03 |
HBsAg > 250 IU/mL | 19 (21.8%) | 9 (40.9%) | 0.07 |
HBsAg seroconversion | 11 (12.6%) | 0 (0%) | 0.08 |
HBeAg positive | 8 (9.2%) | 3 (13.6%) | 0.54 |
HBeAg seroconversion | 72 (82.8%) | 15 (68.2%) | 0.13 |
HBV DNA >1000 copies/mL | 11 (12.6%) | 1 (4.5%) | 0.28 |
Final follow-up | |||
Months from disease onset to examination | 7.0 ± 0.8 (5.2-8.3) | 6.9 ± 0.7 (5.8-8.2) | 0.54 |
HBsAg positive | 4 (4.6%) | 4 (18.2%) | 0.03 |
HBsAg > 250 IU/mL | 1 (1.1%) | 1 (4.5%) | 0.29 |
HBsAg seroconversion | 59 (67.8%) | 9 (40.9%) | 0.02 |
HBeAg positive | 1 (1.1%) | 1 (4.5%) | 0.29 |
HBeAg seroconversion | 80 (91.9%) | 19 (86.3%) | 0.42 |
HBV DNA > 1000 copies/mL | 1 (1.1%) | 1 (4.5%) | 0.29 |