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Table 4 HBV serological and virological data in pregnant and non-pregnant AHB patients at admission, discharge and final follow-up

From: Clinical features and outcome of acute hepatitis B in pregnancy

Variables Non-pregnant AHB patients N = 87 Pregnant AHB patients N = 22 P
At admission    
Days from disease onset to examination 11.8 ± 7.3 11.3 ± 4.1 0.70
HBsAg positive 6 (93.1%) 22 (100%) 0.21
HBsAg > 250 IU/mL 45 (51.7%) 17 (77.3%) 0.03
HBsAg seroconversion 3 (3.44%) 0 (0%) 0.38
HBeAg positive 52 (59.8%) 19 (86.4%) 0.02
HBeAg seroconversion 33 (37.9%) 2 (9.1%) 0.01
HBV DNA (log10 copies/mL) 3.49 (3.0-7.14) 3.49 (3.0-4.93) 0.69
HBV DNA >1000 copies/mL 55 (63.2%) 17 (77.3%) 0.21
At discharge    
Days from disease onset to examination 38.6 ± 11.9 34.2 ± 7.1 0.11
HBsAg positive 54 (62.1%) 19 (86.4%) 0.03
HBsAg > 250 IU/mL 19 (21.8%) 9 (40.9%) 0.07
HBsAg seroconversion 11 (12.6%) 0 (0%) 0.08
HBeAg positive 8 (9.2%) 3 (13.6%) 0.54
HBeAg seroconversion 72 (82.8%) 15 (68.2%) 0.13
HBV DNA >1000 copies/mL 11 (12.6%) 1 (4.5%) 0.28
Final follow-up    
Months from disease onset to examination 7.0 ± 0.8 (5.2-8.3) 6.9 ± 0.7 (5.8-8.2) 0.54
HBsAg positive 4 (4.6%) 4 (18.2%) 0.03
HBsAg > 250 IU/mL 1 (1.1%) 1 (4.5%) 0.29
HBsAg seroconversion 59 (67.8%) 9 (40.9%) 0.02
HBeAg positive 1 (1.1%) 1 (4.5%) 0.29
HBeAg seroconversion 80 (91.9%) 19 (86.3%) 0.42
HBV DNA > 1000 copies/mL 1 (1.1%) 1 (4.5%) 0.29
  1. NOTE. Data are expressed as mean ± SD,median (min-max), or n (%) of patients; HBV, hepatitis B virus; AHB, acute hepatitis B; HBsAg,hepatitis B surface antigen; HBeAg, hepatitis e antigen.