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Table 1 Comparisons of baseline characteristics by new or previously treated cases (n = 669)

From: Predictors of pulmonary tuberculosis treatment outcomes in South Korea: a prospective cohort study, 2005-2012

Variables

Group (%)

P-value

  

New case

Previously treated case

 

Demographic

    

Gender

Female

36 (16.1)

70 (15.7)

0.909

 

Male

188 (83.9)

375 (84.3)

 

Age

20-34

47 (21.0)

122 (27.4)

0.158

 

35-49

95 (42.4)

183 (41.1)

 
 

50-

82 (36.6)

140 (31.5)

 

Health condition

    

BMI (n = 626)

<18.5

108 (50.2)

204 (49.6)

0.887

 

18.5-

107 (49.8)

207 (50.4)

 

Diabetes

No

180 (80.4)

340 (76.4)

0.246

 

Yes

44 (19.6)

105 (23.6)

 

Individual behavior

    

Alcohol, within 6 months

Less than once a week

102 (45.5)

245 (55.1)

0.062

 

Several times a week

39 (17.4)

68 (15.3)

 
 

At least once a day

83 (37.1)

132 (29.7)

 

Smoking, within 6 months

Never smoked

56 (25.0)

125 (28.1)

<0.001

< 1 pack/day

30 (12.39)

125 (28.1)

 

1 pack/day

78 (34.8)

121 (27.2)

 

> 1 pack/day

60 (26.8)

74 (16.6)

 

Socioeconomic

    

Residential area

Small city and town

135 (60.3)

245 (55.1)

0.199

 

Large city

89 (39.7)

200 (44.9)

 

Education

High school, above

120 (53.6)

251 (56.4)

0.487

 

Middle school, below and refusal

104 (46.4)

194 (43.6)

 

Occupation

Health care, professional, office work

16 (7.1)

55 (12.4)

0.117

 

Service sector and laborer in construction or factory

128 (57.1)

242 (54.4)

 
 

Unemployment and others

80 (35.7)

148 (33.3)

 

Housing status (n = 668)

Private

201 (89.7)

415 (93.5)

0.089

 

Other

23 (10.3)

29 (6.5)

 

Tuberculosis-related clinical

    

Chest X ray

    

Grade

Minimal

10 (4.5)

9 (2.0)

0.020

 

Moderately advanced

111 (49.6)

187 (42.0)

 
 

Far advanced

103 (46.0)

249 (56.0)

 

Cavity

Yes

138 (61.6)

281 (63.1)

<0.001

 

No

68 (30.4)

78 (17.5)

 
 

Not clear

18 (8.0)

86 (19.3)

 

Bilateral

Unilateral

57 (25.4)

56 (12.6)

<0.001

 

Bilateral

167 (74.6)

389 (87.4)

 

Nodular lesion

Yes

199 (88.8)

417 (93.7)

0.038*

 

No

22 (9.8)

27 (6.1)

 
 

Not clear

3 (1.3)

1 (0.2)

 

Treatment History

    

Number of previous treatment episode (n = 444)

1

-

151 (33.9)

-

2

-

106 (23.8)

 

3

-

63 (14.2)

 

4 or more

-

125 (28.1)

 

Cumulative duration of previous treatment (days, n = 444)

Median (IQR)

-

304 (61-761)

-

History of failure (n = 445)

No

-

249 (56.0)

-

 

Yes

-

196 (44.0)

 

History of treatment interruption (n = 445)

No

-

207 (46.5)

-

Yes

-

238 (53.5)

 

Drug Susceptibility pattern (n = 581)

DS

146 (75.0)

92 (26.5)

<0.001*

 

Mono/Poly-R

29 (14.8)

44 (11.4)

 
 

Rif, mono-R

4 (2.0)

16 (4.2)

 
 

MDR

16 (8.2)

223 (57.9)

 

AFB smear score at baseline

    

-

1 (0.5)

4 (0.9)

0.689*

Scant

51 (22.8)

85 (19.1)

 
 

1+

121 (54.0)

247 (55.5)

 
 

≥2+

51 (22.8)

109 (24.5)

 
  1. *Tested by Fisher’s exact test.
  2. BMI: Body mass index; DS: Drug susceptible, Mono/poly-R: mono or poly-drug resistance that is not matched with the definition of Multidrug-resistant tuberculosis; MDR: multidrug-resistant tuberculosis.