|
Demographic
| | | | |
|
Gender
|
Female
|
36 (16.1)
|
70 (15.7)
|
0.909
|
| |
Male
|
188 (83.9)
|
375 (84.3)
| |
|
Age
|
20-34
|
47 (21.0)
|
122 (27.4)
|
0.158
|
| |
35-49
|
95 (42.4)
|
183 (41.1)
| |
| |
50-
|
82 (36.6)
|
140 (31.5)
| |
|
Health condition
| | | | |
|
BMI (n = 626)
|
<18.5
|
108 (50.2)
|
204 (49.6)
|
0.887
|
| |
18.5-
|
107 (49.8)
|
207 (50.4)
| |
|
Diabetes
|
No
|
180 (80.4)
|
340 (76.4)
|
0.246
|
| |
Yes
|
44 (19.6)
|
105 (23.6)
| |
|
Individual behavior
| | | | |
|
Alcohol, within 6 months
|
Less than once a week
|
102 (45.5)
|
245 (55.1)
|
0.062
|
| |
Several times a week
|
39 (17.4)
|
68 (15.3)
| |
| |
At least once a day
|
83 (37.1)
|
132 (29.7)
| |
|
Smoking, within 6 months
|
Never smoked
|
56 (25.0)
|
125 (28.1)
|
<0.001
|
|
< 1 pack/day
|
30 (12.39)
|
125 (28.1)
| |
|
1 pack/day
|
78 (34.8)
|
121 (27.2)
| |
|
> 1 pack/day
|
60 (26.8)
|
74 (16.6)
| |
|
Socioeconomic
| | | | |
|
Residential area
|
Small city and town
|
135 (60.3)
|
245 (55.1)
|
0.199
|
| |
Large city
|
89 (39.7)
|
200 (44.9)
| |
|
Education
|
High school, above
|
120 (53.6)
|
251 (56.4)
|
0.487
|
| |
Middle school, below and refusal
|
104 (46.4)
|
194 (43.6)
| |
|
Occupation
|
Health care, professional, office work
|
16 (7.1)
|
55 (12.4)
|
0.117
|
| |
Service sector and laborer in construction or factory
|
128 (57.1)
|
242 (54.4)
| |
| |
Unemployment and others
|
80 (35.7)
|
148 (33.3)
| |
|
Housing status (n = 668)
|
Private
|
201 (89.7)
|
415 (93.5)
|
0.089
|
| |
Other
|
23 (10.3)
|
29 (6.5)
| |
|
Tuberculosis-related clinical
| | | | |
|
Chest X ray
| | | | |
|
Grade
|
Minimal
|
10 (4.5)
|
9 (2.0)
|
0.020
|
| |
Moderately advanced
|
111 (49.6)
|
187 (42.0)
| |
| |
Far advanced
|
103 (46.0)
|
249 (56.0)
| |
|
Cavity
|
Yes
|
138 (61.6)
|
281 (63.1)
|
<0.001
|
| |
No
|
68 (30.4)
|
78 (17.5)
| |
| |
Not clear
|
18 (8.0)
|
86 (19.3)
| |
|
Bilateral
|
Unilateral
|
57 (25.4)
|
56 (12.6)
|
<0.001
|
| |
Bilateral
|
167 (74.6)
|
389 (87.4)
| |
|
Nodular lesion
|
Yes
|
199 (88.8)
|
417 (93.7)
|
0.038*
|
| |
No
|
22 (9.8)
|
27 (6.1)
| |
| |
Not clear
|
3 (1.3)
|
1 (0.2)
| |
|
Treatment History
| | | | |
|
Number of previous treatment episode (n = 444)
|
1
|
-
|
151 (33.9)
|
-
|
|
2
|
-
|
106 (23.8)
| |
|
3
|
-
|
63 (14.2)
| |
|
4 or more
|
-
|
125 (28.1)
| |
|
Cumulative duration of previous treatment (days, n = 444)
|
Median (IQR)
|
-
|
304 (61-761)
|
-
|
|
History of failure (n = 445)
|
No
|
-
|
249 (56.0)
|
-
|
| |
Yes
|
-
|
196 (44.0)
| |
|
History of treatment interruption (n = 445)
|
No
|
-
|
207 (46.5)
|
-
|
|
Yes
|
-
|
238 (53.5)
| |
|
Drug Susceptibility pattern (n = 581)
|
DS
|
146 (75.0)
|
92 (26.5)
|
<0.001*
|
| |
Mono/Poly-R
|
29 (14.8)
|
44 (11.4)
| |
| |
Rif, mono-R
|
4 (2.0)
|
16 (4.2)
| |
| |
MDR
|
16 (8.2)
|
223 (57.9)
| |
|
AFB smear score at baseline
| | | | |
|
-
|
1 (0.5)
|
4 (0.9)
|
0.689*
|
|
Scant
|
51 (22.8)
|
85 (19.1)
| |
| |
1+
|
121 (54.0)
|
247 (55.5)
| |
| |
≥2+
|
51 (22.8)
|
109 (24.5)
| |
