Characteristics | VRE cases (n = 116) | VSE cases (n = 116) | Controls (n = 116) |
---|---|---|---|
Age, median (IQR), years | 60 (47–68) | 63.5 (51–76) | 58 (44–68) |
Sex | Â | Â | Â |
  Male | 69 (59) | 72 (62) | 63 (54) |
  Female | 47 (41) | 44 (38) | 53 (46) |
Unit of admission | Â | Â | Â |
  Haematology/oncology | 61 (53) | 43 (37) | 67 (58) |
  Non-haematology/oncology | 55 (47) | 73 (63) | 49 (42) |
Reason for admission | |||
  Medical | 89 (77) | 87 (75) | 89 (77) |
  Surgical | 27 (23) | 29 (25) | 27 (23) |
Charlson score, median (IQR) | 4 (2–5) | 3 (1–5) | 4 (1–4) |
Chronic disease score-VRE (CDS-VRE), median (IQR) | 1 (0–1.9) | 0 (0–1) | 0 (0–1.6) |
Lung disease | 17 (15) | 17 (15) | 17 (15) |
Ischaemic heart disease | 25 (22) | 23 (20) | 11 (9) |
Myocardial infarction | 10 (9) | 10 (9) | 3 (3) |
Congestive heart failure | 13 (11) | 14 (12) | 2 (2) |
Cerebrovascular disease | 7 (6) | 13 (11) | 5 (4) |
Gastrointestinal disease | 54 (47) | 64 (55) | 38 (33) |
Renal disease | 21 (18) | 18 (16) | 15 (13) |
Diabetes mellitus | 25 (22) | 30 (26) | 20 (17) |
Cancer | 74 (64) | 64 (55) | 74 (64) |
Solid organ transplant recipient | 14 (12) | 7 (6) | 5 (4) |
Enterococcus species | Â | Â | Â |
  E. faecalis | 9 (8) | 71 (61) | - |
  E. faecium | 107 (92) | 39 (34) | - |
  E. casseliflavus, E. gallinarum, or E. durans | - | 4 (3) | - |
  Both E. faecalis and E. faecium | - | 1 (1) | - |
  Unknown | - | 1 (1) | - |
Polymicrobial bacteraemia | 33 (28) | 50 (43) | - |
Infection (other than due to Enterococci) prior to bacteraemia (VRE and VSE cases) and prior to discharge (controls) | 61 (53) | 43 (37) | 34 (29) |
Days from admission until bacteraemia, median (IQR), days | 16 (7–24) | 7.5 (1–18.5) | - |
Total length of stay, median (IQR), days | 35 (22.5-50.5) | 25 (16–45.5) | 9 (5–20) |
In-hospital mortality | 42 (36) | 30 (26) | 5 (4) |