Table 2 Body composition, adipokines and hormones related to body composition in HIV-infected patients, according to gender
| Â | Male | Female | P |
|---|---|---|---|
n | 144 | 73 | Â |
Age [years, mean (SD)] | 46.8 (11.2) | 46.2 (12.5) | 0.72 |
BMI [(kg/m2), mean (SD)] | 24.7 (3.8) | 26.1 (5.6) | 0.05 |
Waist circumference [cm, mean (SD)] | 91.2 (10.6) | 91.2 (13.5) | 0.98 |
Hip circumference [cm, mean (SD)] | 93.1 (6.7) | 97.2 (10.5) | 0.003 |
Total fat mass CT [cm3, mean (SD)] | 243.4 (136.2) | 356.0 (166.7) | <0.001 |
VAT CT [cm3, mean (SD)] | 140.7 (86.2) | 113.6 (69.9) | 0.02 |
SAT CT [cm3, mean (SD)] | 102.6 (76.9) | 242.4 (125.7) | <0.001 |
VAT/SAT ratio | 2.2 (2.4) | 0.55 (0.40) | <0.001 |
Total fat mass DXA [%, mean (SD)] | 16.8 (8.1) | 33.3 (10.0) | <0.001 |
Trunk fat in DXA [%, mean (SD)] | 20.6 (9.8) | 33.4 (10.3) | <0.001 |
Leg fat mass DXA [%, mean (SD)] | 12.2 (9.1) | 31.9 (12.5) | <0.001 |
Arm fat mass DXA [%, mean (SD)] | 15.2 (8.9) | 42.3 (11.4) | <0.001 |
Adiponectin [μg/mL, median (25th and 75th percentile)] | 3.34 (1.79-6.59) | 3.00 (1.36-6.55) | 0.39 |
Leptin [ng/mL, median (25th and 75th percentile)] | 3.0 (1.8-5.8) | 11.2 (5.7-18.0) | <0.001 |
Resistin [ng/mL, median (25th and 75th percentile)] | 11.2 (8.4-17.0) | 11.2 (8.9-16.8) | 0.42 |
Ghrelin [pg/mL, median (25th and 75th percentile)] | 55.5 (26.9-99.2) | 44.0 (21.4-79.2) | 0.07 |
PAI-1 [pg/mL, median (25th and 75th percentile)] | 61.3 (38.5-104.3) | 43.4 (30.8-95.8) | 0.37 |
TNF-α [pg/mL, median (25th and 75th percentile)] | 49.9 (31.6-72.4) | 39.7 (27.2-60.0) | 0.03 |
Adiponectin/leptin ratio, median (25th and 75th percentile) | 0.945 (0.34-2.04) | 0.245 (0.09-0.63) | <0.001 |