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Table 3 The association between IL-23R variants and susceptibility to IRIS

From: A non-synonymous polymorphism in IL-23R Gene (rs1884444) is associated with reduced risk to schistosomiasis-associated Immune Reconstitution Inflammatory Syndrome in a Kenyan population

IRIS

Genotypes

OR

95% CI

P-value

rs7530511

   

CC

1.00

  

CT

1.05

0.30–3.68

0.308

TT

3.64

0.30–43.62

0.386

rs1884444

   

GG

1.00

  

GT

0.24

0.04–1.51

0.129

TT

0.25

0.07–0.96

0.043

rs11465754

   

AA

1.00

  

AG

0.40

0.12–1.33

0.136

GG

0.37

0.07–1.84

0.222

rs6682925

   

CC

1.00

  

GG

1.95

0.64–5.94

0.240

GG

0.77

0.16–3.81

0.748

rs7539625

   

GG

1.00

  

GA

0.34

0.10–1.14

0.080

AA

0.25

0.05–1.40

0.116

  1. Data are presented as Odds Ratio (OR) and 95% Confidence Interval (95% CI). Data analyzed by multivariate logistic regression analyses controlling for the confounding effects of age and sex.
  2. P-values in bold are significant at P ≤ 0.05. The reference group in each of the analysis was the most prevalent genotype.
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BMC Infectious Diseases

ISSN: 1471-2334

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