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Table 3 Select hospitalization outcomes among the matched cohorts by high-risk group

From: Hospital days, hospitalization costs, and inpatient mortality among patients with mucormycosis: a retrospective analysis of US hospital discharge data

  High-risk group1
Characteristic (A) Severely immunocompromised (B) Critically ill (C) Mildly/moderately immunocompromised (D) Major surgery or Pneumonia
Mucormycosis Cohort     
 N (weighted) 2,623 1,067 1,364 292
 Length of stay (days)     
  Mean (SD) 25.6 (34.0) 35.6 (37.9) 14 (15.7) 22.5 (30.59)
  Median (IQR) 15 (6–32) 25 (10–45) 8 (4–20) 16 (8–24)
 Mortality (%) 23.4% 35.3% 9.4% 21.3%
 Total Charges     
  Mean (SD) $255,708 ($292,863) $361,607 ($366,468) $124,187 ($140,931) $174,256 ($183,497)
  Median (IQR) $140,867 ($54,693 - $345,646) $216,589 ($93,922 - $525,537) $68,281 ($27,062 - $161,126) $108,226 ($61,543 - $225,011)
 Total Costs     
  Mean (SD) $98,365 ($117,047) $134,082 ($145,047) $46,923 ($54,558) $73,748 ($75,906)
  Median (IQR) $56,267 ($22,533 - $122,632) $85,106 ($33,613 - $173,195) $24,546 ($10,542 - $62,435) $45,832 ($20,356 - $92,340)
Non-mucormycosis Cohort     
 N (weighted) 7,839 3,488 3,804 867
 Length of stay (days)     
  Mean (SD) 8.2 (10.67) 10.9 (17.9) 5.3 (6.12) 5.6 (7.8)
  Median (IQR) 5 (3–9) 6 (3–13) 4 (2–6) 3 (2–6)
 Mortality (%) 3.7% 9.6% 1.5% 1.7%
 Total Charges     
  Mean (SD) $77,591 ($125,386) $96,878 ($136,883) $38,373 ($48,383) $62,714 ($77,071)
  Median (IQR) $36,391 ($17,814 - $83,945) $45,347 ($20,938 - $110,051) $24,693 ($13,589 - $44,194) $37,087 ($21,023 - $70,037)
 Total Costs     
  Mean (SD) $28,301 ($45,397) $32,694 ($48,476) $14,393 ($18,339) $25,568 ($32,338)
  Median (IQR) $13,229 ($6,618 - $31,261) $15,488 ($7,820 - $36,035) $9,094 ($5,168 - $16,155) $14,343 ($7,534 - $31,615)
  1. Source: HCUP 2003–2010.
  2. [1] All high-risk groups were mutually exclusive. Severely immunocompromised (A) conditions include leukemia/lymphoma/HSCT/BMT, chemotherapy, other immune disorders, solid organ transplant or long-term steroid use. Critically ill (B) conditions include trauma, septicemia, bacteremia, necrotizing fasciitis, intracranial hemorrhage and mechanical ventilation for 96+ hours. Mildly/moderately immunocompromised (C) conditions include ESRD/hemodialysis, lupus, malignant solid tumors, diabetic ketoacidosis, blood disorders, and diabetes. Major surgery or pneumonia (D) includes selected thoracic, cardiac, vascular, abdominal, peripheral, urology, and neurology surgeries, other major procedures, and pneumonia.
  3. Note: Charges and costs reported in 2011 USD.