Table 3 Demographic and clinical characteristics of patients with K. pneumoniae blood stream infections stratified by survivors versus non-survivors
Variable | Survived (n = 63) | Died (n = 12) | p-value |
|---|---|---|---|
Age (mean, SD) | 58.8 (16.6) | 64 (11.7) | 0.30 |
Gender, female | 32 (50.8) | 8 (66.7) | 0.36 |
Modified APACHE II score (mean, SD) | 10.6 (4.3) | 13.2 (4.9) | 0.07 |
Prior hospitalization | 29 (46) | 11 (91.7) | <0.01 |
Neutropenic | 2 (3.2) | 0 (0) | 0.99 |
Renal dysfunction | 7 (11.1) | 6 (50) | <0.01 |
Liver dysfunction | 6 (9.5) | 1 (8.3) | 0.99 |
Diabetes | 7 (11.1) | 4 (33.3) | 0.07 |
Current immunosuppressive therapy | 10 (15.9) | 2 (16.7) | 0.99 |
LOS prior to positive culture (median, IQR) | 1 (1–1) | 10.5 (2.5-23) | <0.01 |
Time to directed therapy (hrs) (median, IQR) | 6 (3–15.5) | 0 (0–5.25) | <0.01 |
K. pneumoniae cultured from >1 site | 24 (38.1) | 6 (50) | 0.44 |
Total days of antibiotics post infection (median, IQR) | 7 (4–14) | 9 (5–15.5) | 0.56 |
KPC(+) status | 10 (15.9) | 5 (41.7) | 0.055 |