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Table 1 Characteristics of 229 HIV-infected patients co-infected with tuberculosis

From: The impact of HAART initiation timing on HIV-TB co-infected patients, a retrospective cohort study

 

Died (n = 60, 26.2%)

Survived (n = 169)

Total (n = 229)

TB diagnosis year

   

  1997–2000

12 (20.3%)

47 (79.7%)

59 {25.8%}

  2001–2003

19 (29.2%)

46 (70.8%)

65 {28.4%}

  2004–2006

29 (27.6%)

76 (72.4%)

105 {45.9%}

Age (yrs) at first TB diagnosis, median [IQR]$

42.1 [33.3-53.5]

36.8 [32.4-43.6]

37.5 [32.5-47.1]

  Male

55 (25.6%)

160 (74.4%)

215 {93.9%}

  Female

5 (35.7%)

9 (64.3%)

14 {6.1%}

HIV transmission category

   

  MSM

18 (20.0%)

72 (80.0%)

90 {39.3%}

  Heterosexual contacts

33 (39.7%)

78 (70.3%)

111 {48.5%}

  IDUs

4 (19.1%)

17 (81.0%)

21 {9.2%}

  Other/undefined

5 (71.4%)

2 (28.6%)

7 {3.1%}

CD4 count (/mm3) at TB diagnosis, median [IQR]

22 [7-85]

43 [20-117]

40 [17-107]

  ≤50

32 (25.2%)

95 (74.8%)

127 {55.5%}

  51–100

9 (25.0%)

27 (75.0%)

36 {15.7%}

  101–200

8 (33.3%)

16 (66.7%)

24 {10.5%}

  ≥200

3 (9.7%)

28 (90.3%)

31 {13.5%}

  No data

8 (72.7%)

3 (27.3%)

11 {4.8%}

Localization of tuberculosis

   

  Pulmonary

22 (26.8%)

60 (73.2%)

82 {35.8%}

  PTB+ extra-pulmonary

37 (28.2%)

94 (71.8%)

131 {57.2%}

  Extra-pulmonary

1 (6.3%)

15 (93.8%)

20 {7.0%}

Laboratory findings

   

  Positive AFS smear

46 [76.7%]

127 [75.2%]

173 {75.6%}

  Positive MTB culture

49 [81.7%]

139 [82.3%]

188 {82.1%}

HAART during anti-TB treatment$

   

  No

30 (66.7%)

15 (33.3%)

45 {19.7%}

  Yes

30 (16.3%)

154 (83.7%)

184 {80.3%}

IRIS*

5 (8.8%)

52 (91.2%)

57 {31.0%}*

HBV (+)#

7 [11.7%]

29 [17.2%]

36 {15.7%}

HCV (+)#

5 [8.3%]

22 [13.0%]

27 {11.8%}

  1. Data are presented as n (% of the category) unless otherwise indicated. {%} indicated as the proportion of the total reported cases. [%] indicated as the proportion in the subgroup.
  2. Abbreviations: IQR interquartile range, PTB pulmonary tuberculosis. AFS acid-fast stain, MTB Mycobacterium tuberculosis, MSM men who had sex with men, IDUs injecting drug users, HAART highly active antiretroviral therapy, IRIS Immune reconstitution inflammatory syndrome, HBV hepatitis B virus infection, HCV hepatitis C virus infection.
  3. *Only cases started HAART were counted as denominator.
  4. #Only 156 and 144 patients had available HBV and HCV examination results respectively.
  5. $ p < 0.01.