Association between adherence to an antimicrobial stewardship program and mortality among hospitalised cancer patients with febrile neutropaenia: a prospective cohort study

Table 4 Multivarate logistic model of baseline factors significantly associated with antimicrobial treatment according ASP guideline

Variables	Odds ratio	95% CI	P-value
Age, years	1.03	1.007–1.06	0.01
Clinical comorbidity	0.40	0.18–0.89	0.02
Hypotension at the time of diagnosis of FN	0.04	0.01–0.15	<0.001
Diarrhoea at the time of diagnosis of FN	0.05	0.02–0.11	<0.001
Perianal pain at the time of diagnosis of FN	0.07	0.02–0.21	<0.001
Suspected source of oral cavity infections	0.05	0.01–0.22	<0.001
Cutaneous manifestations of infection	0.04	0.01–0.11	<0.001

Note: Variables entered into the model: age, clinical comorbidity, ANC at the time of the diagnosis of FN, nosocomial-acquired FN, antibiotic use in the previous 30 days, high-risk MASCC score, hypotension at the time of diagnosis of FN, diarrhoea at the time of diagnosis of FN, perianal pain at the time of diagnosis of FN, suspected source of oral cavity infections, and cutaneous manifestations of infection.
CI, confidence interval.

ISSN: 1471-2334