Table 2 Annual incidence rates per 100 person-years of severe morbid events, AIDS and non-AIDS events, and deaths, overall and by cohort (ANRS CO3 Aquitaine and IPEC/FIOCRUZ cohorts)
2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | P-value | |
|---|---|---|---|---|---|---|---|---|---|---|
Overall | ||||||||||
Severe morbid event | 27.3 | 26.4 | 20.5 | 21.2 | 20.3 | 19.4 | 18.0 | 19.1 | 19.2 | < 0.01 |
AIDS | 6.2 | 5.7 | 5.0 | 4.4 | 5.1 | 4.6 | 3.6 | 3.8 | 4.3 | < 0.01 |
Non-AIDS | 21.1 | 20.7 | 15.5 | 16.7 | 15.2 | 14.8 | 14.4 | 15.3 | 14.9 | < 0.01 |
Death | 1.9 | 2.7 | 2.3 | 2.2 | 2.5 | 2.6 | 2.0 | 2.0 | 1.5 | < 0.01 |
ANRS CO3 Aquitaine | ||||||||||
Severe morbid event | 26.2 | 25.2 | 18.7 | 18.9 | 18.7 | 17.6 | 17.8 | 20.0 | 18.2 | < 0.01 |
AIDS | 4.7 | 4.4 | 3.1 | 2.7 | 2.9 | 2.5 | 1.9 | 2.5 | 2.0 | < 0.01 |
Non-AIDS | 21.6 | 20.8 | 15.6 | 16.2 | 15.8 | 15.2 | 15.9 | 17.5 | 16.2 | 0.04 |
Death | 1.6 | 2.3 | 2.2 | 1.7 | 1.6 | 1.9 | 1.5 | 1.3 | 1.1 | < 0.01 |
IPEC/FIOCRUZ | ||||||||||
Severe morbid event | 31.4 | 30.5 | 26.2 | 27.8 | 24.6 | 23.9 | 18.3 | 17.3 | 20.9 | < 0.01 |
AIDS | 12.0 | 10.2 | 11.1 | 9.5 | 10.9 | 10.1 | 7.3 | 6.4 | 8.2 | < 0.01 |
Non-AIDS | 19.4 | 20.4 | 15.1 | 18.3 | 13.6 | 13.7 | 11.0 | 10.8 | 12.7 | < 0.01 |
Death | 3.0 | 4.0 | 2.6 | 3.6 | 4.7 | 4.2 | 3.0 | 3.3 | 2.3 | 0.09 |