Table 1 Demographics and patient characteristics
Characteristics | MRSA pneumonia n = 134 (%) | Non-MRSA pneumonia n = 134 (%) | p value |
|---|---|---|---|
Demographics | |||
Age [median (IQR)] | 82 (71.5, 89) | 75.5 (62, 85) | 0.0002 |
Male | 67 (50) | 62 (46) | 0.62 |
Residence prior to admission | |||
Home | 35 (26) | 110 (82) | < 0.0001 |
SNF | 98 (73) | 23 (17) | < 0.0001 |
Other hospital | 1 (0.7) | 1 (0.7) | 1 |
APACHE II [median (IQR)] | 15 (11,20) | 10 (7,13) | <0.0001 |
Comorbid conditions | |||
Cardiovascular diseasea | 92 (69) | 84 (63) | 0.37 |
Diabetes | 44 (33) | 26 (19) | <0.0001 |
Cerebrovascular accident (CVA) | 41 (31) | 9 (7) | <0.0001 |
Liver diseaseb | 6 (4) | 4 (3) | 0.74 |
Renal diseasec | 22 (16) | 8 (6) | 0.011 |
Pulmonary diseased | 47 (35) | 39 (29) | 0.24 |
Malignancy | 21 (16) | 14 (10) | 0.37 |
≥3 comorbid conditions | 86 (64) | 40 (30) | <0.0001 |
Healthcare exposure history | |||
History of MRSA infection | 27 (20) | 1 (0.7) | <0.0001 |
History of MRSA pneumonia | 14 (10) | 0 | <0.0001 |
Prior healthcare exposure (within 90 days) | 120 (90) | 50 (37) | <0.0001 |
Prior antibiotic exposure (within 90 days) | 70 (52) | 23 (17) | <0.0001 |
Days since last antibiotic given [median (IQR)] | 24 (7,41) | 7 (0,32) | 0.629 |
Prior history of pneumonia within 1 year | 56 (42) | 16 (12) | <0.0001 |
Presence of feeding tube | 67 (50) | 15 (11) | <0.0001 |
Presence of feeding tube plus history of CVA | 26 (19) | 4 (3) | <0.0001 |
Clinical presentation | |||
Presence of other infections on admission | 55 (41) | 13 (10) | <0.0001 |
Admission of intensive care units | 63 (47) | 18 (13) | <0.0001 |
Sepsis requiring vasopressor support | 45 (34) | 8 (6) | <0.0001 |
Need for mechanical ventilation | 47 (35) | 14 (10) | <0.0001 |
PSI class IV or V | 123 (92) | 71 (53) | <0.0001 |