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Table 2 Infectious diseases and malignancies in AIDS-associated autopsies

From: The prevalence of opportunistic infections and malignancies in autopsied patients with human immunodeficiency virus infection in Japan

  All patients ART (−) patients ART (+) patients   
  n % n % n % Pvalues  
Total 225 100.0% 136 100.0% 66 100.0%   
Infectious diseases         
  Cytomegalovirus 142 63.1% 97 71.3% 25 37.9% <0.001  
  Pneumocystis jirovecii pneumonia 66 29.3% 43 31.6% 11 16.7% 0.024  
  Non-tuberculous mycobacterium 31 13.8% 20 14.7% 8 12.1% 0.618  
  Candida 25 11.1% 17 12.5% 6 9.1% 0.474  
  Aspergillus 24 10.7% 17 12.5% 4 6.1% 0.160  
  Human immunodeficiency virus encephalopathy 21 9.3% 13 9.6% 6 9.1% 0.915  
  Cryptococcus 16 7.1% 11 8.1% 3 4.5% 0.526 Y
  Hepatitis B virus 12 5.3% 6 4.4% 5 7.6% 0.549 Y
  Herpes simplex virus 12 5.3% 1 0.7% 1 1.5% 0.816 Y
  Toxoplasmosis 11 4.9% 9 6.6% 3 4.5% 0.789 Y
  Hepatitis C virus 9 4.0% 3 2.2% 5 7.6% 0.147 Y
  Progressive multifocal leukoencephalopathy 8 3.6% 4 2.9% 2 3.0% 0.684 Y
  Tuberculosis 6 2.7% 4 2.9% 0 0.0% 0.385 Y
  Varicella zoster virus 4 1.8% 2 1.5% 2 3.0% 0.835 Y
  Multicentric Castleman disease 2 0.9% 1 0.7% 1 1.5% 0.816 Y
Malignancies         
  Non Hodgkin lymphoma 71 31.6% 41 30.1% 25 37.9% 0.272  
  Kaposi sarcoma 38 16.9% 22 16.2% 10 15.2% 0.852  
  Endocervical cancer 0 0.0% 0 0.0% 0 0.0%  
  Non-AIDS defining malignancies 20 8.9% 10 7.4% 10 15.2% 0.082  
   Hepatic cancer 8 3.6% 4 2.9% 4 6.1% 0.495 Y
   Lung cancer 6 2.7% 2 1.5% 4 6.1% 0.174 Y
   Leukemia 2 0.9% 0 0.0% 2 3.0% 0.200 Y
   Hodgkin lymphoma 2 0.9% 1 0.7% 1 1.5% 0.816 Y
   Gastric cancer 1 0.4% 1 0.7% 0 0.0% 0.711 Y
   Other cancer 3 1.3% 3 2.2% 0 0.0% 0.551 Y
  1. P values were calculated by Chi-square test. Y indicates the use of Chi-square test with Yates correction. Bold font indicates statistical significance. ART, antiretroviral therapy. Because more than one illness was detected in patients, the numbers of all illness are greater than the total number.