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Table 1 Urgency of source control intervention (after [23])

From: How to treat infections in a surgical intensive care unit

Level of urgency Timing of intervention Context
1 <1-2 h after diagnosis Rapidly progressive disease e.g. necrotizing fasciitis, intra-abdominal infection with abdominal compartment syndrome
2 As soon as patient physiology allows Limited deferral is acceptable provided antibiotics are administered and patient is not deteriorating e.g. peritonitis
3 As soon as infectious process has demarcated Adequate source control is facilitated and probability of collateral damage lower e.g. infected pancreatic necrosis in a stable patient