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Table 2 GFR (ml/min/1.73 m 2 ) results using MDRD over follow up

From: Higher risk of renal impairment associated with tenofovir use amongst people living with HIV in India: A comparative cohort analysis between Western India and United Kingdom

  Baseline 6 mths 12 mths 18 mths 24 mths
Royal Free patients      
Number with measure 574 514 468 364 273
GFR Mean (SD) 104 (25) 100 (23) 99 (22) 97 (21) 97 (25)
Change from baseline - -4 (19) -6 (18) -6 (19) -7 (21)
GFR <90 150 (26.1) 169 (32.9) 178 (38.0) 128 (35.2) 110 (40.3)
GFR < 60 10 (1.7) 7 (1.4) 8 (1.7) 9 (2.5) 11 (4.0)
GFR < 30 1 (0.2) 1 (0.2) 2 (0.4) 2 (0.6) 0 (0.0)
P-value for change from baseline   <0.0001    <0.0001
IID, Pune patients      
Number with measure 702 439 391 366 302
GFR Mean (SD) 105 (35) 97 (28) 96 (28) 98 (29) 96 (31)
Change from baseline   -6 (39) -7 (38) -8 (40) -7 (40)
GFR <90 254 (36.2) 193 (44.0) 195 (49.9) 165 (45.1) 144 (47.7)
GFR < 60 38 (5.4) 28 (6.4) 27 (6.9) 32 (8.7) 23 (7.6)
GFR < 30 2 (0.3) 0 (0.0) 2 (0.5) 2 (0.6) 2 (0.7)
P-value for change from baseline   <0.0001    0.001
P-value for comparison of centres   0.46    0.76