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Table 2 GFR (ml/min/1.73 m 2 ) results using MDRD over follow up

From: Higher risk of renal impairment associated with tenofovir use amongst people living with HIV in India: A comparative cohort analysis between Western India and United Kingdom

 

Baseline

6 mths

12 mths

18 mths

24 mths

Royal Free patients

     

Number with measure

574

514

468

364

273

GFR Mean (SD)

104 (25)

100 (23)

99 (22)

97 (21)

97 (25)

Change from baseline

-

-4 (19)

-6 (18)

-6 (19)

-7 (21)

GFR <90

150 (26.1)

169 (32.9)

178 (38.0)

128 (35.2)

110 (40.3)

GFR < 60

10 (1.7)

7 (1.4)

8 (1.7)

9 (2.5)

11 (4.0)

GFR < 30

1 (0.2)

1 (0.2)

2 (0.4)

2 (0.6)

0 (0.0)

P-value for change from baseline

 

<0.0001

  

<0.0001

IID, Pune patients

     

Number with measure

702

439

391

366

302

GFR Mean (SD)

105 (35)

97 (28)

96 (28)

98 (29)

96 (31)

Change from baseline

 

-6 (39)

-7 (38)

-8 (40)

-7 (40)

GFR <90

254 (36.2)

193 (44.0)

195 (49.9)

165 (45.1)

144 (47.7)

GFR < 60

38 (5.4)

28 (6.4)

27 (6.9)

32 (8.7)

23 (7.6)

GFR < 30

2 (0.3)

0 (0.0)

2 (0.5)

2 (0.6)

2 (0.7)

P-value for change from baseline

 

<0.0001

  

0.001

P-value for comparison of centres

 

0.46

  

0.76