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Table 4 Incidence rates of hospitalizations for infectious diseases in the Inpatient Register for individuals previously discharged with a COPD diagnosis and control subjects from the general population

From: Increased incidence of invasive bacterial disease in chronic obstructive pulmonary disease compared to the general population-a population based cohort study

 

COPD

Control subjects

 

Type of infection

N

Incidence1

N

Incidence1

HR2

Pnemonia

8,581

983 (963–1,004)

2,638

188 (181–195)

4.7 (4.4-4.9)

Skin infection

698

80 (74–86)

331

24 (21–26)

3.3 (2.8-3.8)

CNS infection

18

2.0 (1.3-3.2)

23

1.6 (1.1-2.4)

1.1 (0.6-2.3)3

Endocarditis

60

6.9 (5.3-8.9)

34

2.4 (1.7-3.4)

2.8 (1.7-4.7)

Pyelonephritis

500

57 (52–62)

300

22 (20–24)

2.4 (2.0-2.9)

Septic arthritis

93

10.7 (9.7-13.1)

80

5.7 (4.6-7.1)

1.9 (1.3-2.6)

  1. 1- Crude incidence of hospitalizations for infectious diseases per 10,000 person-years of follow-up. Infectious episodes were separated by >30 days for pneumonia, skin infection, CNS infection and pyelonephritis and >60 days for endocarditis and septic arthritis. 2-Hazard ratio of time to first hospitalization for infection estimated by Cox regression using time since inclusion as the time scale and stratified for age, year of birth and gender and adjusted for socio-economic status and co-morbidity. 3-Due to the limited number of outcomes, this Cox model was only adjusted for any co-morbidity (yes/no) prior to inclusion.