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Table 4 Incidence rates of hospitalizations for infectious diseases in the Inpatient Register for individuals previously discharged with a COPD diagnosis and control subjects from the general population

From: Increased incidence of invasive bacterial disease in chronic obstructive pulmonary disease compared to the general population-a population based cohort study

  COPD Control subjects  
Type of infection N Incidence1 N Incidence1 HR2
Pnemonia 8,581 983 (963–1,004) 2,638 188 (181–195) 4.7 (4.4-4.9)
Skin infection 698 80 (74–86) 331 24 (21–26) 3.3 (2.8-3.8)
CNS infection 18 2.0 (1.3-3.2) 23 1.6 (1.1-2.4) 1.1 (0.6-2.3)3
Endocarditis 60 6.9 (5.3-8.9) 34 2.4 (1.7-3.4) 2.8 (1.7-4.7)
Pyelonephritis 500 57 (52–62) 300 22 (20–24) 2.4 (2.0-2.9)
Septic arthritis 93 10.7 (9.7-13.1) 80 5.7 (4.6-7.1) 1.9 (1.3-2.6)
  1. 1- Crude incidence of hospitalizations for infectious diseases per 10,000 person-years of follow-up. Infectious episodes were separated by >30 days for pneumonia, skin infection, CNS infection and pyelonephritis and >60 days for endocarditis and septic arthritis. 2-Hazard ratio of time to first hospitalization for infection estimated by Cox regression using time since inclusion as the time scale and stratified for age, year of birth and gender and adjusted for socio-economic status and co-morbidity. 3-Due to the limited number of outcomes, this Cox model was only adjusted for any co-morbidity (yes/no) prior to inclusion.