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Table 5 Number of positive samples and median Crossing point (Cp) values of all bacteria detected by Septifast PCR, grouped into severe sepsis/septic shock and non-severe sepsis cases

From: Quantitative data from the SeptiFast real-time PCR is associated with disease severity in patients with sepsis

Species identified by Septifast Severe sepsis/septic shock Non severe sepsis P-value for comparison between groups
  No. of cases Cp median (range) No. of cases Cp median (range)  
Gram positive bacteria 17 16.7 (7.3-21.7) 25 19.9 (8.8-22.2) 0.007
Staphylococcus aureus 8 16.8 (10.4-21.7) 16 20.3 (13.0-22.2) 0.045
Streptococcus speciesa 5 16.6 (14.7-16.8) 8 18.5 (17.0-19.9) 0.002
Enterococcus faecalis 2 18.1 (17.1-19.2) 1 8.8 NRb
Streptococcus pneumoniae 2 13.5 (7.3-19.8) 0   NR
Gram negative bacteria 13 17.1 (11.2-24.3) 44 21.9 (8.5-25.0) 0.004
Escherichia coli 8 16.4 (13.7-22.6) 25 21.0 (17.8-25.0) 0.006
Klebsiella pneumoniae/oxytoca 2 14.1 (11.2-17.0) 11 22.8 (20.9-25.0) NR
Enterobacter cloacae/aerogenes 2 23.6 (23.0-24.3) 3 20.5 (8.5-25.0) NR
Pseudomonas aeruginosa 1 21.6 4 23.2 (19.2-25.0) NR
Serratia marcescens 0   1 23.3 NR
Total 30 16.9 (7.3-24.3) 69 20.9 (8.5-25.0) <0.001
  1. Comparison of median Cp values between groups.
  2. a Streptococcus pyogenes, S. agalactiae and S. mitis bNot relevant, due to small numbers.