Table 4 Clinical characteristics and detailed history of precipitating immunosuppressive agents in 12 sporadic non-clustered cases of hospital-associated listeriosis
Case | Underlying disease | Cause of admission | D 1a | Clinical syndrome of listeriosis | Type of precipitating immunosuppressive agent | D 2b | Cause of precipitating immunosuppressive agent |
|---|---|---|---|---|---|---|---|
1 | Breast cancer with liver and lung metastasis | Scheduled chemotherapy | 10 | Primary bacteremia | Corticosteroid and chemotherapy with epirubicin and paclitaxel | 9 | Scheduled chemotherapy |
2 | Hepatic cell carcinoma with multiple bone metastasis | Management of low back pain | 14 | Primary bacteremia | Corticosteroid | 7 | Management of paraplegia caused by hepatic cell carcinoma with spine metastasis |
3 | Systemic lupus erythematosus | Management of pregnancy complicated with pre-eclampsia | 59 | Meningitis and bacteremia | Corticosteroid and chemotherapy with cyclophosphamide | 17 | Pulse therapy for lupus nephritis with flare-up |
4 | Lymphocytic myocarditis complicated with congestive heart failure | Management of acute pulmonary edema | 59 | Meningitis and bacteremia | Corticosteroid and chemotherapy with cyclophosphamide | 23 | Pulse therapy for lymphocytic myocarditis |
5 | New diagnosis of pancreatic cancer with lung metastasis | Evaluation of lung mass | 30 | Primary bacteremia | Corticosteroid and chemotherapy with cyclophosphamide | 22 | For suspected Wegner’s granuloma |
6 | New diagnosis of left adrenal gland with pancreas tail invasion and multiple bone metastasis | Evaluation of abdominal pain | 42 | Primary bacteremia | Nil | Nil | Â |
7 | Lung cancer | Management of obstructive pneumonia | 18 | Primary bacteremia | Corticosteroid | 4 | Management of paraplegia caused by lung cancer with spine metastasis |
8 | New diagnosis of acute lymphoblastic leukemia | Evaluation of petechiae and bruising over extremity | 10 | Primary bacteremia | Corticosteroid and chemotherapy with cystarabine, methotrexate, vincristine and asparaginase | 11 | Induction chemotherapy for acute lymphoblastic leukemia |
9 | Ischemic heart disease complicated with congestive heart failure | Management of acute pulmonary edema caused by fluid overload | 13 | Primary bacteremia | Corticosteroid | 12 | For suspected superimposed chronic obstructive pulmonary disease with flare-up |
10 | New diagnosis of multiple myeloma | Evalaution of oliguria | 51 | Primary bacteremia | Corticosteroid | 27 | Management of paraplegia caused by multiple myeloma with spinal compression |
11 | Diffuse large B cell lymphoma | Scheduled chemotherapy | 11 | Primary bacteremia | Corticosteroid and chemotherapy with methotrexate, rituximab and gemcitabine | 10 | Scheduled chemotherapy |
12 | Nasopharyngeal carcinoma with skull bone metastasis | Management of hypercalcemia caused by malignancy | 52 | Primary bacteremia | Corticosteroid | 14 | Management of drug allergy caused by nonsteroidal anti-inflammatory drug |