Table 2 Changes from M0 to M24 in plasma markers of inflammation and immune activation (log _e -transformed values)

1.6 (1.1-2.5)

1.6 (1.1-2.6)

1.2 (0.99-1.7)

1.6 (1.1-2.5)

1.2 (0.88-2.4)

2.17 (1.1-7.4)

0.60 (0.49, 0.74)

0.60 (0.48, 0.77)

0.60 (0.36, 0.99)

0.59 (0.42, 0.83)

0.82 (0.64, 1.05)

0.36 (0.20, 0.67)

<0.001

4 (2.2-15)

4.2 (2.3-15)

2.7 (1.8-9.4)

3.9 (2.2-17.8)

3 (2-5.9)

7.5 (2.9-20)

0.77 (0.57, 1.1)

0.81 (0.56, 1.20)

0.66 (0.33, 1.30)

0.76 (0.46, 1.26)

0.88 (0.54, 1.44)

0.63 (0.27, 1.47)

0.11

2.6 (2.1-3.1)

2.6 (2.2-3.1)

2.5 (2-3.1)

2.5 (2.2-3)

2.6 (1.7-3.1)

3.1 (2-3.4)

1.00 (0.93, 1.1)

1.00 (0.93, 1.10)

0.96 (0.79, 1.15)

0.95 (0.85, 1.06)

1.10 (0.93, 1.26)

1.00 (0.85, 1.20)

0.82

664 (431-960)

630 (435-974)

721 (431-895)

692 (447-996)

549 (389-781)

798 (470-1326)

0.41 (0.35, 0.49)

0.44 (0.36, 0.52)

0.37 (0.27, 0.49)

0.34 (0.28, 0.42)

0.53 (0.40, 0.71)

0.43 (0.27, 0.67)

<0.001

1532 (980-2804)

1534 (1004-2804)

1431 (938-2562)

1908 (1093-3799)

1182 (920-2201)

1611 (887-2444)

0.26 (0.19, 0.33)

0.25 (0.18, 0.35)

0.27 (0.17, 0.42)

0.16 (0.10, 0.24)

0.39 (0.30, 0.51)

0.39 (0.22, 0.70)

<0.001