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Table 3 Diagnostic accuracy of urine LAM testing for clinically suspected active tuberculosis

From: Diagnostic accuracy of a point-of-care urine test for tuberculosis screening among newly-diagnosed hiv-infected adults: a prospective, clinic-based study

 

N

Sensitivity (95% CI)

Specificity (95% CI)

LR positive (95% CI)

LR negative (95% CI)

Positive PV (95% CI)

Negative PV (95% CI)

Urine LAM

 All participants

92

25.0% (16.6-35.1)

91.2% (87.0-94.4)

2.84 (1.67-4.84)

0.82 (0.73-0.93)

51.1% (35.8-66.3)

76.8% (71.5-81.5)

  CD4 ≥ 100 cells/mm3

35

22.8% (10.4-40.1)

92.7% (87.3-96.3)

3.14 (1.36-7.22)

0.83 (0.69-1.00)

42.1% (20.3-66.5)

83.8% (77.4-89.1)

  CD4 < 100 cells/mm3

47

27.7% (15.6-42.6)

84.8% (71.1-93.7)

1.82 (0.80-4.14)

0.85 (0.69-1.06)

65.0% (40.8-84.6)

53.4% (41.4-65.2)

  1. LR = likelihood ratio; PV = predictive value; CI = confidence interval.