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Table 1 Demographic & clinical information about pediatric TB suspects, N = 118

From: Intensified specimen collection to improve tuberculosis diagnosis in children from Rural South Africa, an observational study

  Total Possible TB Probable & Culture-confirmed TB p-value
  n = 118, (%) n = 85, (%) n = 33, (%)  
Age, mean years [SD] 4.7 [3.1] 4.9 [3.4] 4.4 [3.2] NS
Female gender, n (%) 53 (45) 39 (46) 14 (42) NS
Mother as primary caregiver 70 (59) 50 (59) 20 (61) NS
Either parent deceased 37 (31) 26 (31) 11 (33) NS
HIV-infected mother 50 (42) 35 (41) 15 (45) NS
Other HIV-infected family member 9 (8) 7 (8) 2 (6) NS
TB contact reported 62 (53) 37 (44) 25 (76) 0.001
Drug-resistant TB contact reported 4 (3) 3 (3) 1 (3) NS
Contact with “chronic cougher” 19 (16) 13 (15) 6 (18) NS
Prior TB 37 (31) 28 (33) 9 (28) NS
Prior hospitalization (≥1) 31 (26) 24 (28) 7 (21) NS
Malnourished 52 (44) 34 (40) 18 (55) NS
Severely malnourished (n, % of malnourished) 42 (81) 26 (76) 16 (89) 0.09
Tested for HIV 99 (84) 73 (86) 26 (79) NS
HIV positive 64 (65) 47 (64) 17 (65) NS
On HAART, n (% of HIV+) 32 (50) 25 (53) 7 (41) NS
CD4%, median [IQR] 16.8 [11.5-22.3] 16.7 [13.7-22.3] 17 [7.28-19.2] NS
Hemoglobin, median g/dL [IQR] 9.9 [8.8-11.2] 10.3 [9.2-11.2] 8.9 [7.3-10.8] 0.04
Albumin, median g/L [IQR] 32.0 [28.1-37.0] 33.9 [29.0-37.0] 28.8 [25.0-30.8] NS
Erythrocyte Sedimentation Rate, median [IQR] 32.0 [14.0-75.0] 30.0 [14.0-75.0] 36.0 [13.5-75.0] NS
Abnormal chest radiograph consistent with TB 84* (85) 55* (79) 29* (100) 0.03
Enrolled while failing ≥2 mo TB treatment 8 (7) 6 (7) 2 (6) NS
Started on TB treatment 59 (50) 37 (44) 22 (67) NS
  1. *Of 99 children with chest radiographs available for review.