Table 1 Demographic & clinical information about pediatric TB suspects, N = 118
Total | Possible TB | Probable & Culture-confirmed TB | p-value | |
|---|---|---|---|---|
n = 118, (%) | n = 85, (%) | n = 33, (%) | ||
Age, mean years [SD] | 4.7 [3.1] | 4.9 [3.4] | 4.4 [3.2] | NS |
Female gender, n (%) | 53 (45) | 39 (46) | 14 (42) | NS |
Mother as primary caregiver | 70 (59) | 50 (59) | 20 (61) | NS |
Either parent deceased | 37 (31) | 26 (31) | 11 (33) | NS |
HIV-infected mother | 50 (42) | 35 (41) | 15 (45) | NS |
Other HIV-infected family member | 9 (8) | 7 (8) | 2 (6) | NS |
TB contact reported | 62 (53) | 37 (44) | 25 (76) | 0.001 |
Drug-resistant TB contact reported | 4 (3) | 3 (3) | 1 (3) | NS |
Contact with “chronic cougher” | 19 (16) | 13 (15) | 6 (18) | NS |
Prior TB | 37 (31) | 28 (33) | 9 (28) | NS |
Prior hospitalization (≥1) | 31 (26) | 24 (28) | 7 (21) | NS |
Malnourished | 52 (44) | 34 (40) | 18 (55) | NS |
Severely malnourished (n, % of malnourished) | 42 (81) | 26 (76) | 16 (89) | 0.09 |
Tested for HIV | 99 (84) | 73 (86) | 26 (79) | NS |
HIV positive | 64 (65) | 47 (64) | 17 (65) | NS |
On HAART, n (% of HIV+) | 32 (50) | 25 (53) | 7 (41) | NS |
CD4%, median [IQR] | 16.8 [11.5-22.3] | 16.7 [13.7-22.3] | 17 [7.28-19.2] | NS |
Hemoglobin, median g/dL [IQR] | 9.9 [8.8-11.2] | 10.3 [9.2-11.2] | 8.9 [7.3-10.8] | 0.04 |
Albumin, median g/L [IQR] | 32.0 [28.1-37.0] | 33.9 [29.0-37.0] | 28.8 [25.0-30.8] | NS |
Erythrocyte Sedimentation Rate, median [IQR] | 32.0 [14.0-75.0] | 30.0 [14.0-75.0] | 36.0 [13.5-75.0] | NS |
Abnormal chest radiograph consistent with TB | 84* (85) | 55* (79) | 29* (100) | 0.03 |
Enrolled while failing ≥2 mo TB treatment | 8 (7) | 6 (7) | 2 (6) | NS |
Started on TB treatment | 59 (50) | 37 (44) | 22 (67) | NS |