Volume 13 Supplement 1

Proceedings of the 9th Edition of the Scientific Days of the National Institute for Infectious Diseases “Prof Dr Matei Bals”

Open Access

Helicobacter pyloriinfection in HIV-positive patients from the Mureş regional center

  • Nina-Ioana Șincu1Email author,
  • Lucia Carmen Chiriac1,
  • Brînduşa Ţilea1,
  • Erzsebet Iringo Zaharia-Kezdi1,
  • Anca Meda Georgescu1,
  • Cristina Gârbovan1,
  • Andrea Incze1,
  • Andreea Bodea2 and
  • Simona Bățagă3
BMC Infectious Diseases201313(Suppl 1):P75

https://doi.org/10.1186/1471-2334-13-S1-P75

Published: 16 December 2013

Background

Helicobacter pylori, responsible for one of the most frequent infections on the globe, was reported by several literature studies to be less frequent among patients infected with human immunodeficiency virus (HIV), especially at low levels of CD4+ T-cells. The purpose of the study was to evaluate the features of Helicobacter pylori infection in HIV-positive patients from the Mureş regional center.

Methods

We performed a retrospective, descriptive study, over a 3-year period (August 2010 – August 2013), on 63 HIV-positive patients with dyspeptic symptoms, tested for Helicobacter pylori infection in the Laboratory of Infectious Diseases, Clinical County Hospital Mureş.

Results

Seventeen (26.98%) HIV-positive patients were co-infected with Helicobacter pylori. The average level of CD4+ T-lymphocytes was 292 cells/µL in Helicobacter pylori-positive patients and 312 cells/µL in Helicobacter pylori-negative ones, which did not result in a statistically significant difference regarding the level of CD4+ T-cells (p=0.8785).

Conclusion

Our study showed a frequency of Helicobacter pylori-HIV co-infection of 26.98% among HIV-positive patients monitored in the regional center Mureş, without statistically significant differences regarding the level of CD4+ T-cells.

Declarations

Acknowledgement

This paper is partly supported by the Sectorial Operational Programme Human Resources Development (SOP HRD), financed from the European Social Fund and by the Romanian Government under the contract number POSDRU 80641.

Authors’ Affiliations

(1)
Department of Infectious Diseases, University of Medicine and Pharmacy Tîrgu Mureş
(2)
Clinic of Infectious Diseases I, Clinical County Hospital Mureş
(3)
Department of Internal Medicine I, University of Medicine and Pharmacy Tîrgu Mureş

Copyright

© Șincu et al; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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