Volume 13 Supplement 1

Proceedings of the 9th Edition of the Scientific Days of the National Institute for Infectious Diseases “Prof Dr Matei Bals”

Open Access

New cases of HIV/AIDS in adults during 2007-2012

  • Andreea Cristina Stoian1, 2Email author,
  • Constantin Bănică2,
  • Loredana Ionescu2,
  • Augustin Cupşa1, 2,
  • Lucian Giubelan1, 2 and
  • Florentina Dumitrescu1, 2
BMC Infectious Diseases201313(Suppl 1):P6

https://doi.org/10.1186/1471-2334-13-S1-P6

Published: 16 December 2013

Background

We analyzed the epidemiological and clinical aspects in patients newly diagnosed with HIV.

Methods

We performed a retrospective, compared study, in the Regional Monitoring and Evaluation of HIV/AIDS from Craiova, between 01 January 2007 – 31 December 2012, in two groups of patients with HIV/AIDS, as follows: group A-59 patients diagnosed with HIV/AIDS in the period 01 January 2010 – 31 December 2012 and group B-113 patients diagnosed with HIV/AIDS in the period 01 January 2007 – 31 December 2009, the results analyzed were: clinical, epidemiological, immunological and virological evolution in the first 12 months of screening. For statistical analysis we used the Epi Info program, threshold (p) values are statistically significant at ≤0.05.

Results

Demographic data for group A vs. group B: female/male = 16 (27.11%) / 43 (72.88%) vs. 61 (53.98%) / 52 (46.02%); p=0.0011, urban/rural = 30 (50.84%) / 29 (49.15%) vs. = 65 (57.52%) / 48 (42.47%), p=0.42; probable route of transmission: sexual/horizontal, in early childhood / i.v. drugs = 49 (83.05%) / 9 (15.24%) / 1 (1.69%) vs. 62 (50.44%) / 51 (45.13%) p=0.002; the average age (years): 31.2±10.98 vs. 24.5±12.25; p=0.0005; the average CD4 count = 323.14±161.57 vs. 209.22±104.61 cells/cmm; p=0.86, the average HIV viral load = 5.4 log copies/mL vs. 4.9 log copies/mL, clinical and immunological distribution: B3 = 11 (18.64%) vs. 18 (15.92%), C3 = 15 (25.42%) vs. 43 (38.05%), the symptomatic/asymptomatic onset = 45 (76.27%) / 14 (23.72%) vs. 80 (70.79%) / 33 (29.20%); p=0.47, the most common opportunistic infection is pulmonary tuberculosis = 19 (32.20%) vs. 31 (27.43%); p=0.59; administration of ART: 45 (76.27%) vs. 80 (70.79%); deaths in the first 12 months of detection = 2 (3.38%) vs. 3 (2.65%); p =1.000.

Conclusion

The new cases of HIV infection in 2007-2009 were lower than during 2010-2012, when the route of sexual transmission was predominant, male sex is more commonly affected, and the average age is elder. Mortality remained at a low rate, but similar in both periods followed (2007-2009 vs. 2010-2012). Tuberculosis was the most common opportunistic infection in HIV detection, independently of the period followed.

Authors’ Affiliations

(1)
University of Medicine and Pharmacy Craiova
(2)
“Victor Babeş” Clinical Hospital of Infectious Diseases and Pneumology

Copyright

© Stoian et al; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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