Volume 13 Supplement 1

Proceedings of the 9th Edition of the Scientific Days of the National Institute for Infectious Diseases “Prof Dr Matei Bals”

Open Access

HPV infection in ENT - certainties and assumptions

  • Loredana Mitran1Email author,
  • Mihai Mitran2,
  • Daniela Safta1,
  • Sorin Puia2 and
  • Carmen Georgescu2
BMC Infectious Diseases201313(Suppl 1):P111

https://doi.org/10.1186/1471-2334-13-S1-P111

Published: 16 December 2013

Background

HPV infection is considered the most frequent sexually transmitted infection. The clinical manifestations of infection are various and variable, including the ones in ENT, such as recurrent laryngeal papillomatosis and tonsillar cancer.

Case report

We present the possibilities of diagnosis of HPV infection in ENT, and the therapeutic, prophylactic and curative modalities, as well as the assumptions and prevention goals through vaccination within this specialty. We communicate the management of three clinical cases of laryngeal papillomatosis in adults.

The first case, a 75-year-old woman, 4 times under surgical intervention with “cold surgery”, vaccinated with Silgard. The second case, a 55-year-old woman, also 4 times under surgical intervention receives Gardasil after the last intervention. The third case, a 35-year-old man, 2 times surgically operated after diagnosed with papiloma scuamosis and vaccined with Silgard.

All the above mentioned cases don’t present any regression of the disease during the last three years.

Conclusion

The involvement of HPV in ENT cancer pathology is undeniable. Laryngeal papillomatosis is a precancerous condition caused by HPV strains 6 and 11. HPV vaccination can be useful both to prevent HPV-induced pathology in otolaryngology and after surgery, to prevent recurrence.

Authors’ Affiliations

(1)
Elias University Emergency Hospital
(2)
Clinical Hospital of Obstetrics and Gynecology “Prof. Dr. Panait Sârbu”

Copyright

© Mitran et al; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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