Volume 13 Supplement 1

Proceedings of the 9th Edition of the Scientific Days of the National Institute for Infectious Diseases “Prof Dr Matei Bals”

Open Access

Pregnancy and birth in HIV seropositive women - present stage results

  • Mihai Mitran1Email author,
  • Carmen Georgescu1,
  • Mariana Mărdărescu2,
  • Bogdan Marinescu1,
  • Andreea Velişcu1,
  • Ioana Roşca1 and
  • Marcela Șerban3
BMC Infectious Diseases201313(Suppl 1):O34

https://doi.org/10.1186/1471-2334-13-S1-O34

Published: 16 December 2013

Background

Since 1992, the Clinical Hospital of Obstetrics and Gynecology “Prof. Dr. Panait Sârbu”, Bucharest has been the medical unit to consult, record and monitor pregnancies, births and miscarriages associated with transmittable diseases - including HIV positive patients - from Bucharest and the surrounding counties, as the hospital had the necessary professional expertise and intrahospital networks. In time, within the “Prof. Dr. Panait Sârbu” Clinic, we have systematized and implemented an obstetric protocol for the prevention of HIV vertical transmission.

Methods

The aim of this protocol has been to reduce the HIV vertical transmission rate from 30-35%, the value in 2000, to 2-3%, the rate recorded in the European developed countries.

Starting from the primordial objective to decrease mother-to-child vertical transmission rate, we established the cesarean section as the method of delivery for all HIV positive women, at 37-38 weeks, on intact membranes, outside labor. The result was a significant decrease in the number of HIV positive babies.

Results

The results of the past 7 years have been most encouraging, with a 0 rate of vertical transmission through C-section, and a 23.63% transmission for vaginal delivery.

Conclusion

Attentive monitoring of pregnancy by the obstetrician in cooperation with the infectious diseases specialist, delivery by C-section, complex antiretroviral therapy for both mother and child and ablactation have been the main means through which a spectacular decrease in HIV vertical transmission has been achieved.

Authors’ Affiliations

(1)
Clinical Hospital of Obstetrics and Gynecology “Prof. Dr. Panait Sârbu”
(2)
National Institute for Infectious Diseases "Prof. Dr. Matei Balş"
(3)
The Institute for Mother and Child Protection “Alfred Rusescu”

Copyright

© Mitran et al; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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