Figure 3

Incidence of overall per dose solicited local (pain, redness, and swelling) and general (drowsiness, fever, irritability, and loss of appetite) symptoms of any intensity and grade 3 intensity reported during the 4-day post-vaccination period (total vaccinated cohort). Footnote: PHiD-CV group= infants vaccinated with PHiD-CV co-administered with DTPa-HBV-IPV/Hib at 2, 3, and 4 months of age. Control group= infants vaccinated with DTPa-HBV-IPV/Hib at 2, 3, and 4 months of age. Grade 3 symptoms: pain if the infant was crying when the limb was moved or if the limb was spontaneously painful, redness or swelling if the diameter was >30 mm, drowsiness if it prevented normal activity, fever if axillary temperature was >39.5°C, irritability if the infant was crying and could not be comforted or if it prevented normal activity, and loss of appetite if the infant did not eat at all. Error bars indicate 95% confidence intervals.