Table 1 Isolates from IPD in children from Germany from July 1997 to June 2011, proportion of serotype 19A and antibiotic resistance among serotype 19A isolates
From: Epidemiology of serotype 19A isolates from invasive pneumococcal disease in German children
Number of isolates per season | Number of serotype | Number of 19A isolates resistant* (%) | |||||
|---|---|---|---|---|---|---|---|
Season | 19A (%) | PEN I+R | CLA R | CLI R | TET R | MDR | |
Pre-PCV vaccination period | |||||||
1997-1998 | 167 | 7 (4.2) | 1 (14.3) | 1 (14.3) | 0 (0.0) | 1 (14.3) | 0 (0.0) |
1998-1999 | 152 | 6 (3.9) | 2 (33.3) | 1 (16.7) | 1 (16.7) | 1 (16.7) | 1 (16.7) |
1999-2000 | 190 | 6 (3.2) | 1 (16.7) | 2 (33.3) | 2 (33.3) | 3 (50.0) | 2 (33.3) |
2000-2001 | 238 | 5 (2.1) | 0 (0.0) | 1 (20.0) | 1 (20.0) | 1 (20.0) | 1 (20.0) |
2001-2002 | 241 | 7 (2.9) | 3 (42.9) | 1 (14.3) | 1 (14.3) | 2 (28.6) | 1 (14.3) |
2002-2003 | 239 | 4 (1.7) | 0 (0.0) | 1 (25.0) | 1 (25.0) | 0 (0.0) | 1 (25.0) |
2003-2004 | 272 | 6 (2.2) | 2 (33.3) | 1 (16.7) | 1 (16.7) | 1 (16.7) | 0 (0.0) |
2004-2005 | 286 | 11 (3.8) | 5 (45.5) | 4 (36.4) | 3 (27.3) | 5 (45.5) | 2 (18.2) |
2005-2006 | 291 | 6 (2.1) | 2 (33.3) | 2 (33.3) | 1 (16.7) | 4 (66.7) | 1 (16.7) |
Total | 2076 | 58 (2.8#) | 16 (27.6†) | 14 (24.1) | 11 (19.0) | 18 (31.0) | 9 (15.5) |
Post-PCV vaccination period (PCV7) | |||||||
2006-2007 | 295 | 12 (4.1) | 3 (25.0) | 5 (41.7) | 5 (41.7) | 6 (50.0) | 5 (41.7) |
2007-2008 | 241 | 11 (4.6) | 4 (36.4) | 2 (18.2) | 1 (9.1) | 4 (36.4) | 1 (9.1) |
2008-2009 | 249 | 19 (7.6) | 12 (63.2) | 5 (26.3) | 4 (21.1) | 8 (42.1) | 5 (26.3) |
Post-PCV vaccination period (PCV10, PCV7/13) | |||||||
2009-2010 | 233 | 24 (10.3) | 11 (45.8) | 7 (29.2) | 7 (29.2) | 6 (25.0) | 7 (29.2) |
2010-2011 | 234 | 35 (15.0) | 8 (22.9) | 8 (22.9) | 8 (22.9) | 7 (20.0) | 8 (22.9) |
Total (post PCV) | 1252 | 101 (9.9#) | 38 (37.6†) | 27 (26.7) | 25 (24.8) | 31 (30.7) | 26 (25.7) |