Table 1 Baseline characteristics (n = 873)
From: Hyponatremia and anti-diuretic hormone in Legionnaires’ disease
Parameter | All CAP patients | Legionnaires’ disease | Other CAP etiology | p |
|---|---|---|---|---|
n = 873 | n = 27 | n = 846 | ||
Demographics | ||||
Age (years), mean (SD) | 68.3 (±0.6) | 64.9 (±3.1) | 68.4 (±0.6) | 0.35 |
Male gender, n (%) | 512 (58.7%) | 20 (74.1%) | 492 (58.2%) | 0.09 |
Comorbidities, n (%) | ||||
Congestive heart failure | 151 (17.3%) | 2 (7.4%) | 149 (17.6%) | 0.16 |
COPD | 266 (30.5%) | 3 (11.1%) | 263 (31.1%) | 0.03 |
Diabetes | 149 (17.1%) | 6 (22.2%) | 143 (16.9%) | 0.47 |
Tumor | 109 (12.5%) | 2 (7.4%) | 107 (12.7%) | 0.42 |
Chronic renal failure | 195 (22.3%) | 7 (25.9%) | 188 (22.2%) | 0.65 |
Clinical presentation, mean (SD) | ||||
Heart rate (beats/min) | 95.7 (±0.7) | 101.3 (±3.9) | 95.5 (±0.7) | 0.12 |
Blood pressure systolic (mmHg) | 133.1 (±0.8) | 136.5 (±4.1) | 133 (±0.8) | 0.45 |
Respiratory rate (breaths/min) | 22.1 (±0.3) | 25.7 (±3.4) | 22 (±0.3) | 0.052 |
Temperature (°C) | 38 (±0.1) | 38.7 (±0.2) | 38 (±0.1) | 0.012 |
Blood analysis on admission, mean (SD) | ||||
Sodium (mmol/l) | 135.3 (±0.2) | 131.6 (±0.9) | 135.4 (±0.2) | <0.001 |
Sodium < 130 mmol/l, n (%) | 81 (9.3%) | 12 (44.4%) | 69 (8.2%) | <0.001 |
C-reactive protein (mg/l) | 178.4 (±4.5) | 334.2 (±23.6) | 173.4 (±4.4) | <0.001 |
Procalcitonin (µg/l) | 4.4 (±0.5) | 4.1 (±0.9) | 4.4 (±0.5) | 0.92 |
CT-ProVasopressin (pmol/l) | 50.9 (±2.6) | 39.4 (±7) | 51.2 (±2.7) | 0.43 |
Risk scores on admission, mean (SD) | ||||
PSI score | 92 (±1.2) | 101.4 (±6) | 91.7 (±1.2) | 0.17 |
CURB65 score | 1.5 (±0) | 1.4 (±0.2) | 1.5 (±0) | 0.61 |
Hospital outcomes | ||||
Mortality, n (%) | 49 (5.6%) | 2 (7.4%) | 47 (5.6%) | 0.68 |
ICU admission, n (%) | 79 (9.1%) | 9 (33.3%) | 70 (8.3%) | <0.001 |
Length of stay (days), mean (SD) | 9.8 (±0.3) | 12.3 (±1.8) | 9.7 (±0.3) | 0.09 |